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Microcrystallography, high-pressure cryocooling and BioSAXS at MacCHESS
The Macromolecular Diffraction Facility at the Cornell High Energy Synchrotron Source (MacCHESS) is a national research resource supported by the National Center for Research Resources of the US National Institutes of Health. MacCHESS is pursuing several research initiatives designed to benefit both...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004259/ https://www.ncbi.nlm.nih.gov/pubmed/21169696 http://dx.doi.org/10.1107/S0909049510036010 |
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author | Englich, Ulrich Kriksunov, Irina A. Cerione, Richard A. Cook, Michael J. Gillilan, Richard Gruner, Sol M. Huang, Qingqui Kim, Chae Un Miller, William Nielsen, Soren Schuller, David Smith, Scott Szebenyi, Doletha M. E. |
author_facet | Englich, Ulrich Kriksunov, Irina A. Cerione, Richard A. Cook, Michael J. Gillilan, Richard Gruner, Sol M. Huang, Qingqui Kim, Chae Un Miller, William Nielsen, Soren Schuller, David Smith, Scott Szebenyi, Doletha M. E. |
author_sort | Englich, Ulrich |
collection | PubMed |
description | The Macromolecular Diffraction Facility at the Cornell High Energy Synchrotron Source (MacCHESS) is a national research resource supported by the National Center for Research Resources of the US National Institutes of Health. MacCHESS is pursuing several research initiatives designed to benefit both CHESS users and the wider structural biology community. Three initiatives are presented in further detail: microcrystallography, which aims to improve the collection of diffraction data from crystals a few micrometers across, or small well diffracting regions of inhomogeneous crystals, so as to obtain high-resolution structures; pressure cryocooling, which can stabilize transient structures and reduce lattice damage during the cooling process; and BioSAXS (small-angle X-ray scattering on biological solutions), which can extract molecular shape and other structural information from macromolecules in solution. |
format | Text |
id | pubmed-3004259 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-30042592010-12-23 Microcrystallography, high-pressure cryocooling and BioSAXS at MacCHESS Englich, Ulrich Kriksunov, Irina A. Cerione, Richard A. Cook, Michael J. Gillilan, Richard Gruner, Sol M. Huang, Qingqui Kim, Chae Un Miller, William Nielsen, Soren Schuller, David Smith, Scott Szebenyi, Doletha M. E. J Synchrotron Radiat Diffraction Structural Biology The Macromolecular Diffraction Facility at the Cornell High Energy Synchrotron Source (MacCHESS) is a national research resource supported by the National Center for Research Resources of the US National Institutes of Health. MacCHESS is pursuing several research initiatives designed to benefit both CHESS users and the wider structural biology community. Three initiatives are presented in further detail: microcrystallography, which aims to improve the collection of diffraction data from crystals a few micrometers across, or small well diffracting regions of inhomogeneous crystals, so as to obtain high-resolution structures; pressure cryocooling, which can stabilize transient structures and reduce lattice damage during the cooling process; and BioSAXS (small-angle X-ray scattering on biological solutions), which can extract molecular shape and other structural information from macromolecules in solution. International Union of Crystallography 2011-01-01 2010-11-05 /pmc/articles/PMC3004259/ /pubmed/21169696 http://dx.doi.org/10.1107/S0909049510036010 Text en © Ulrich Englich et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Diffraction Structural Biology Englich, Ulrich Kriksunov, Irina A. Cerione, Richard A. Cook, Michael J. Gillilan, Richard Gruner, Sol M. Huang, Qingqui Kim, Chae Un Miller, William Nielsen, Soren Schuller, David Smith, Scott Szebenyi, Doletha M. E. Microcrystallography, high-pressure cryocooling and BioSAXS at MacCHESS |
title | Microcrystallography, high-pressure cryocooling and BioSAXS at MacCHESS |
title_full | Microcrystallography, high-pressure cryocooling and BioSAXS at MacCHESS |
title_fullStr | Microcrystallography, high-pressure cryocooling and BioSAXS at MacCHESS |
title_full_unstemmed | Microcrystallography, high-pressure cryocooling and BioSAXS at MacCHESS |
title_short | Microcrystallography, high-pressure cryocooling and BioSAXS at MacCHESS |
title_sort | microcrystallography, high-pressure cryocooling and biosaxs at macchess |
topic | Diffraction Structural Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004259/ https://www.ncbi.nlm.nih.gov/pubmed/21169696 http://dx.doi.org/10.1107/S0909049510036010 |
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