Cargando…
Improvement in the quality of hematopoietic prostaglandin D synthase crystals in a microgravity environment
Human hematopoietic prostaglandin synthase, one of the better therapeutic target enzymes for allergy and inflammation, was crystallized with 22 inhibitors and in three inhibitor-free conditions in microgravity. Most of the space-grown crystals showed better X-ray diffraction patterns than the terres...
Autores principales: | Tanaka, Hiroaki, Tsurumura, Toshiharu, Aritake, Kosuke, Furubayashi, Naoki, Takahashi, Sachiko, Yamanaka, Mari, Hirota, Erika, Sano, Satoshi, Sato, Masaru, Kobayashi, Tomoyuki, Tanaka, Tetsuo, Inaka, Koji, Urade, Yoshihiro |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004263/ https://www.ncbi.nlm.nih.gov/pubmed/21169700 http://dx.doi.org/10.1107/S0909049510037076 |
Ejemplares similares
-
High-Quality Protein Crystal Growth of Mouse Lipocalin-Type Prostaglandin D Synthase in Microgravity
por: Inaka, Koji, et al.
Publicado: (2011) -
High-quality crystals of human haematopoietic prostaglandin D synthase with novel inhibitors
por: Takahashi, Sachiko, et al.
Publicado: (2010) -
Optimization of salt concentration in PEG-based crystallization solutions
por: Yamanaka, Mari, et al.
Publicado: (2010) -
Numerical model of protein crystal growth in a diffusive field such as the microgravity environment
por: Tanaka, Hiroaki, et al.
Publicado: (2013) -
JAXA protein crystallization in space: ongoing improvements for growing high-quality crystals
por: Takahashi, Sachiko, et al.
Publicado: (2013)