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Recent Advances in Understanding the Microbiology of the Female Reproductive Tract and the Causes of Premature Birth

Data derived from molecular microbiological investigations of the human vagina have led to the discovery of resident bacterial communities that exhibit marked differences in terms of species composition. All undergo dynamic changes that are likely due to intrinsic host and behavioral factors. Simila...

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Detalles Bibliográficos
Autores principales: Zhou, Xia, Brotman, Rebecca M., Gajer, Pawel, Abdo, Zaid, Schüette, Ursel, Ma, Sam, Ravel, Jacques, Forney, Larry J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004384/
https://www.ncbi.nlm.nih.gov/pubmed/21197076
http://dx.doi.org/10.1155/2010/737425
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author Zhou, Xia
Brotman, Rebecca M.
Gajer, Pawel
Abdo, Zaid
Schüette, Ursel
Ma, Sam
Ravel, Jacques
Forney, Larry J.
author_facet Zhou, Xia
Brotman, Rebecca M.
Gajer, Pawel
Abdo, Zaid
Schüette, Ursel
Ma, Sam
Ravel, Jacques
Forney, Larry J.
author_sort Zhou, Xia
collection PubMed
description Data derived from molecular microbiological investigations of the human vagina have led to the discovery of resident bacterial communities that exhibit marked differences in terms of species composition. All undergo dynamic changes that are likely due to intrinsic host and behavioral factors. Similar types of bacteria have been found in both amniotic fluid and the vagina, suggesting a potential route of colonization. Given that not all of the species involved in intrauterine infections are readily cultivated, it is important that culture-independent methods of analysis must be used to understand the etiology of these infections. Further research is needed to establish whether an ascending pathway from the vagina to the amniotic cavity enables the development of intrauterine infections.
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spelling pubmed-30043842010-12-30 Recent Advances in Understanding the Microbiology of the Female Reproductive Tract and the Causes of Premature Birth Zhou, Xia Brotman, Rebecca M. Gajer, Pawel Abdo, Zaid Schüette, Ursel Ma, Sam Ravel, Jacques Forney, Larry J. Infect Dis Obstet Gynecol Review Article Data derived from molecular microbiological investigations of the human vagina have led to the discovery of resident bacterial communities that exhibit marked differences in terms of species composition. All undergo dynamic changes that are likely due to intrinsic host and behavioral factors. Similar types of bacteria have been found in both amniotic fluid and the vagina, suggesting a potential route of colonization. Given that not all of the species involved in intrauterine infections are readily cultivated, it is important that culture-independent methods of analysis must be used to understand the etiology of these infections. Further research is needed to establish whether an ascending pathway from the vagina to the amniotic cavity enables the development of intrauterine infections. Hindawi Publishing Corporation 2010 2010-12-09 /pmc/articles/PMC3004384/ /pubmed/21197076 http://dx.doi.org/10.1155/2010/737425 Text en Copyright © 2010 Xia Zhou et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Zhou, Xia
Brotman, Rebecca M.
Gajer, Pawel
Abdo, Zaid
Schüette, Ursel
Ma, Sam
Ravel, Jacques
Forney, Larry J.
Recent Advances in Understanding the Microbiology of the Female Reproductive Tract and the Causes of Premature Birth
title Recent Advances in Understanding the Microbiology of the Female Reproductive Tract and the Causes of Premature Birth
title_full Recent Advances in Understanding the Microbiology of the Female Reproductive Tract and the Causes of Premature Birth
title_fullStr Recent Advances in Understanding the Microbiology of the Female Reproductive Tract and the Causes of Premature Birth
title_full_unstemmed Recent Advances in Understanding the Microbiology of the Female Reproductive Tract and the Causes of Premature Birth
title_short Recent Advances in Understanding the Microbiology of the Female Reproductive Tract and the Causes of Premature Birth
title_sort recent advances in understanding the microbiology of the female reproductive tract and the causes of premature birth
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004384/
https://www.ncbi.nlm.nih.gov/pubmed/21197076
http://dx.doi.org/10.1155/2010/737425
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