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A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency

Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder. Bleeding manifestations and clinical findings vary widely, ranging from asymptomatic subjects to patients with hemorrhages that may cause significant handicaps. Treatment has traditionally involved factor VII(FVII) rep...

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Detalles Bibliográficos
Autores principales: Lee, Won Seok, Park, Young Sil
Formato: Texto
Lenguaje:English
Publicado: The Korean Pediatric Society 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004506/
https://www.ncbi.nlm.nih.gov/pubmed/21189963
http://dx.doi.org/10.3345/kjp.2010.53.10.913
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author Lee, Won Seok
Park, Young Sil
author_facet Lee, Won Seok
Park, Young Sil
author_sort Lee, Won Seok
collection PubMed
description Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder. Bleeding manifestations and clinical findings vary widely, ranging from asymptomatic subjects to patients with hemorrhages that may cause significant handicaps. Treatment has traditionally involved factor VII(FVII) replacement therapy using fresh frozen plasma, prothrombin complex concentrates or plasma-derived FVII concentrates. Recombinant activated FVII (NovoSeven®) is currently considered the first-line treatment for replacement therapy of FVII deficiency. Here we present a case of severe intracerebral and intraventricular hemorrhage in a neonate with congenital FVII deficiency.
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spelling pubmed-30045062010-12-28 A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency Lee, Won Seok Park, Young Sil Korean J Pediatr Case Report Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder. Bleeding manifestations and clinical findings vary widely, ranging from asymptomatic subjects to patients with hemorrhages that may cause significant handicaps. Treatment has traditionally involved factor VII(FVII) replacement therapy using fresh frozen plasma, prothrombin complex concentrates or plasma-derived FVII concentrates. Recombinant activated FVII (NovoSeven®) is currently considered the first-line treatment for replacement therapy of FVII deficiency. Here we present a case of severe intracerebral and intraventricular hemorrhage in a neonate with congenital FVII deficiency. The Korean Pediatric Society 2010-10 2010-10-31 /pmc/articles/PMC3004506/ /pubmed/21189963 http://dx.doi.org/10.3345/kjp.2010.53.10.913 Text en Copyright © 2010 by The Korean Pediatric Society http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Won Seok
Park, Young Sil
A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency
title A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency
title_full A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency
title_fullStr A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency
title_full_unstemmed A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency
title_short A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency
title_sort case of intracranial hemorrhage in a neonate with congenital factor vii deficiency
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004506/
https://www.ncbi.nlm.nih.gov/pubmed/21189963
http://dx.doi.org/10.3345/kjp.2010.53.10.913
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