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Altered sensitivity to mechanical stimulation during prolonged subcutaneous administration of endothelin-1 in rats

Cancer pain is often difficult to treat. Growing evidence indicates that chemical mediators secreted by the tumor itself play an important role in the development of cancer pain. One such mediator, endothelin-1 (ET-1) is secreted by different tumor types. Studies have indicated that ET-1 induces spo...

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Detalles Bibliográficos
Autores principales: Hans, Guy, Deseure, Kristof, Vercauteren, Marcel
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004627/
https://www.ncbi.nlm.nih.gov/pubmed/21197295