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Altered sensitivity to mechanical stimulation during prolonged subcutaneous administration of endothelin-1 in rats
Cancer pain is often difficult to treat. Growing evidence indicates that chemical mediators secreted by the tumor itself play an important role in the development of cancer pain. One such mediator, endothelin-1 (ET-1) is secreted by different tumor types. Studies have indicated that ET-1 induces spo...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004627/ https://www.ncbi.nlm.nih.gov/pubmed/21197295 |