Extended-release morphine sulfate in treatment of severe acute and chronic pain

Morphine is the archetypal opioid analgesic. Because it is a short-acting opioid, its use has been limited to the management of acute pain. The development of extended-release formulations have resulted in the increased utilization of morphine in chronic pain conditions. This review documents the hi...

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Detalles Bibliográficos
Autores principales: Balch, Robert J, Trescot, Andrea
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004644/
https://www.ncbi.nlm.nih.gov/pubmed/21197323
http://dx.doi.org/10.2147/JPR.S6529
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author Balch, Robert J
Trescot, Andrea
author_facet Balch, Robert J
Trescot, Andrea
author_sort Balch, Robert J
collection PubMed
description Morphine is the archetypal opioid analgesic. Because it is a short-acting opioid, its use has been limited to the management of acute pain. The development of extended-release formulations have resulted in the increased utilization of morphine in chronic pain conditions. This review documents the history of morphine use in pain treatment, and describes the metabolism, pharmacodynamics, formulations, and efficacy of the currently available extended-release morphine medications.
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spelling pubmed-30046442010-12-30 Extended-release morphine sulfate in treatment of severe acute and chronic pain Balch, Robert J Trescot, Andrea J Pain Res Review Morphine is the archetypal opioid analgesic. Because it is a short-acting opioid, its use has been limited to the management of acute pain. The development of extended-release formulations have resulted in the increased utilization of morphine in chronic pain conditions. This review documents the history of morphine use in pain treatment, and describes the metabolism, pharmacodynamics, formulations, and efficacy of the currently available extended-release morphine medications. Dove Medical Press 2010-09-21 /pmc/articles/PMC3004644/ /pubmed/21197323 http://dx.doi.org/10.2147/JPR.S6529 Text en © 2010 Balch and Trescot, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Balch, Robert J
Trescot, Andrea
Extended-release morphine sulfate in treatment of severe acute and chronic pain
title Extended-release morphine sulfate in treatment of severe acute and chronic pain
title_full Extended-release morphine sulfate in treatment of severe acute and chronic pain
title_fullStr Extended-release morphine sulfate in treatment of severe acute and chronic pain
title_full_unstemmed Extended-release morphine sulfate in treatment of severe acute and chronic pain
title_short Extended-release morphine sulfate in treatment of severe acute and chronic pain
title_sort extended-release morphine sulfate in treatment of severe acute and chronic pain
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004644/
https://www.ncbi.nlm.nih.gov/pubmed/21197323
http://dx.doi.org/10.2147/JPR.S6529
work_keys_str_mv AT balchrobertj extendedreleasemorphinesulfateintreatmentofsevereacuteandchronicpain
AT trescotandrea extendedreleasemorphinesulfateintreatmentofsevereacuteandchronicpain

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