Patient-derived acute myeloid leukemia (AML) bone marrow cells display distinct intracellular kinase phosphorylation patterns

Multiparametric analyses of phospho-protein activation in patients with acute myeloid leukemia (AML) offers a quantitative measure to monitor the activity of novel intracellular kinase (IK) inhibitors. As recent clinical investigation with FMS-like tyrosine-3 inhibitors demonstrated, targeting IK wi...

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Detalles Bibliográficos
Autores principales: Shults, Keith, Flye, Leanne, Green, Lisa, Daly, Thomas, Manro, Jason R, Lahn, Michael
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004659/
https://www.ncbi.nlm.nih.gov/pubmed/21188123

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