Critical appraisal of temozolomide formulations in the treatment of primary brain tumors: patient considerations

Chemotherapy is assuming an increasingly important role in the treatment of malignant gliomas, of which temozolomide (TMZ) is a key part. TMZ belongs to a class of second-generation imidazotetrazinone prodrugs that exhibit linear pharmacokinetics and do not require hepatic metabolism for activation...

Descripción completa

Detalles Bibliográficos
Autores principales: García, Margarita, Clopés, Ana, Bruna, Jordi, Martínez, María, Fort, Eduard, Gil, Miguel
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004664/
https://www.ncbi.nlm.nih.gov/pubmed/21188132

Ejemplares similares

Ejemplares similares