Cargando…

Epigenetic-Genetic Chromosome Dosage Approach for Fetal Trisomy 21 Detection Using an Autosomal Genetic Reference Marker

BACKGROUND: The putative promoter of the holocarboxylase synthetase (HLCS) gene on chromosome 21 is hypermethylated in placental tissues and could be detected as a fetal-specific DNA marker in maternal plasma. Detection of fetal trisomy 21 (T21) has been demonstrated by an epigenetic-genetic chromos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tong, Yu K., Chiu, Rossa W. K., Akolekar, Ranjit, Leung, Tak Y., Lau, Tze K., Nicolaides, Kypros H., Lo, Y. M. Dennis
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004793/ https://www.ncbi.nlm.nih.gov/pubmed/21249119 http://dx.doi.org/10.1371/journal.pone.0015244

Ejemplares similares

Noninvasive Prenatal Diagnosis of Fetal Trisomy 18 and Trisomy 13 by Maternal Plasma DNA Sequencing
por: Chen, Eric Z., et al.
Publicado: (2011)

Systematic Identification of Placental Epigenetic Signatures for the Noninvasive Prenatal Detection of Edwards Syndrome
por: Tsui, Dana W. Y., et al.
Publicado: (2010)

Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study
por: Chiu, Rossa W K, et al.
Publicado: (2011)

Noninvasive Prenatal Diagnosis of Fetal Trisomy 21 by Allelic Ratio Analysis Using Targeted Massively Parallel Sequencing of Maternal Plasma DNA
por: Liao, Gary J. W., et al.
Publicado: (2012)

Translating Dosage Compensation to Trisomy 21
por: Jiang, Jun, et al.
Publicado: (2013)

Placenta-Derived Fetal Specific mRNA Is More Readily Detectable in Maternal Plasma than in Whole Blood
por: Heung, Macy M. S., et al.
Publicado: (2009)

An autosomal trisomy in cattle
por: Lioi, MB, et al.
Publicado: (1995)

Detection of Embryonic Trisomy 21 in the First Trimester Using Maternal Plasma Cell-Free RNA
por: Weiner, Carl P., et al.
Publicado: (2022)

An efficient method for noninvasive prenatal diagnosis of fetal trisomy 13, trisomy 18, and trisomy 21
por: Sun, Xiaohan, et al.
Publicado: (2019)

Non-Invasive Epigenetic Detection of Fetal Trisomy 21 in First Trimester Maternal Plasma
por: Lim, Ji Hyae, et al.
Publicado: (2011)

Maternal Race and Stillbirth: Cohort Study and Systematic Review with Meta-Analysis
por: Arechvo, Anastasija, et al.
Publicado: (2022)

Preeclampsia Prevention by Timed Birth at Term
por: Magee, Laura A., et al.
Publicado: (2023)

An unusual combination of trisomy 21 and partial trisomy 5q.
por: Kim, C. J., et al.
Publicado: (1992)

Clinical utility of noninvasive fetal trisomy (NIFTY) test – early experience
por: Lau, Tze Kin, et al.
Publicado: (2012)

Disease specific characteristics of fetal epigenetic markers for non-invasive prenatal testing of trisomy 21
por: Lim, Ji Hyae, et al.
Publicado: (2014)

Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors
por: Powers, Rani K., et al.
Publicado: (2019)

Noninvasive Fetal Trisomy (NIFTY) test: an advanced noninvasive prenatal diagnosis methodology for fetal autosomal and sex chromosomal aneuploidies
por: Jiang, Fuman, et al.
Publicado: (2012)

Maternal Plasma Fetal DNA Fractions in Pregnancies with Low and High Risks for Fetal Chromosomal Aneuploidies
por: Hudecova, Irena, et al.
Publicado: (2014)

IONA test for first‐trimester detection of trisomies 21, 18 and 13
por: Poon, L. C., et al.
Publicado: (2015)

U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer’s disease due to autosomal dominant genetic mutations and trisomy 21
por: Hales, Chadwick M, et al.
Publicado: (2014)

Maternal Age-Specific Rates for Trisomy 21 and Common Autosomal Trisomies in Fetuses from a Single Diagnostic Center in Thailand
por: Jaruthamsophon, Kanoot, et al.
Publicado: (2016)

Cell‐free fetal DNA coming in all sizes and shapes
por: Chiu, Rossa W. K., et al.
Publicado: (2021)

Tracheal Stenosis and Congenital Heart Disease in Trisomy 21
por: Kylat, Ranjit I
Publicado: (2019)

FetalQuant(SD): accurate quantification of fetal DNA fraction by shallow-depth sequencing of maternal plasma DNA
por: Jiang, Peiyong, et al.
Publicado: (2016)

High Resolution Size Analysis of Fetal DNA in the Urine of Pregnant Women by Paired-End Massively Parallel Sequencing
por: Tsui, Nancy B. Y., et al.
Publicado: (2012)

Fetal alcohol spectrum disorders and their transmission through genetic and epigenetic mechanisms
por: Mead, Edward A., et al.
Publicado: (2014)

Genetic and epigenetic studies of atopic dermatitis
por: Bin, Lianghua, et al.
Publicado: (2016)

Editorial: Genetic, epigenetic and molecular landscaping of puberty
por: Howard, Sasha R., et al.
Publicado: (2023)

Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology
por: Gai, Wanxia, et al.
Publicado: (2021)

iPSC reprogramming-mediated aneuploidy correction in autosomal trisomy syndromes
por: Akutsu, Silvia Natsuko, et al.
Publicado: (2022)

Case report: Detection of fetal trisomy 9 mosaicism by multiple genetic testing methods: Report of two cases
por: Ma, Na, et al.
Publicado: (2023)

Transcriptome Profiling Uncovers Potential Common Mechanisms in Fetal Trisomies 18 and 21
por: Volk, Marija, et al.
Publicado: (2017)

Genetic and epigenetic insights into fetal alcohol spectrum disorders
por: Ramsay, Michèle
Publicado: (2010)

Editorial: Genetics and epigenetics of fetal alcohol spectrum disorders
por: Mason, Stephen, et al.
Publicado: (2015)

Non-invasive prenatal diagnosis of fetal trisomy 21 using cell-free fetal DNA in maternal blood
por: Lim, Ji Hyae, et al.
Publicado: (2013)

Evaluation of Abdominal Fetal Electrocardiography in Early Intrauterine Growth Restriction
por: Velayo, Clarissa L., et al.
Publicado: (2017)

Widespread Transcriptional Autosomal Dosage Compensation in Drosophila Correlates with Gene Expression Level
por: McAnally, Ashley A., et al.
Publicado: (2010)

Cell‐free DNA screening for rare autosomal trisomies and segmental chromosome imbalances
por: Raymond, Yvette C., et al.
Publicado: (2022)

Mediation of Drosophila autosomal dosage effects and compensation by network interactions
por: Malone, John H, et al.
Publicado: (2012)

Biochemical Screening for Fetal Trisomy 21: Pathophysiology of Maternal Serum Markers and Involvement of the Placenta
por: Guibourdenche, Jean, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ll08vi5il1133r2ft0c63qlibs