Cargando…
Investigation of DNA damage response and apoptotic gene methylation pattern in sporadic breast tumors using high throughput quantitative DNA methylation analysis technology
BACKGROUND-: Sporadic breast cancer like many other cancers is proposed to be a manifestation of abnormal genetic and epigenetic changes. For the past decade our laboratory has identified genes involved in DNA damage response (DDR), apoptosis and immunesurvelliance pathways to influence sporadic bre...
Autores principales: | Pal, Ranjana, Srivastava, Niloo, Chopra, Rupali, Gochhait, Sailesh, Gupta, Pawan, Prakash, Neeraj, Agarwal, Gaurav, Bamezai, Rameshwar NK |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004830/ https://www.ncbi.nlm.nih.gov/pubmed/21092294 http://dx.doi.org/10.1186/1476-4598-9-303 |
Ejemplares similares
-
miR-24-2 controls H2AFX expression regardless of gene copy number alteration and induces apoptosis by targeting antiapoptotic gene BCL-2: a potential for therapeutic intervention
por: Srivastava, Niloo, et al.
Publicado: (2011) -
Implication of BRCA2 -26G>A 5' untranslated region polymorphism in susceptibility to sporadic breast cancer and its modulation by p53 codon 72 Arg>Pro polymorphism
por: Gochhait, Sailesh, et al.
Publicado: (2007) -
mtDNA germ line variation mediated ROS generates retrograde signaling and induces pro-cancerous metabolic features
por: Singh, Rajnish Kumar, et al.
Publicado: (2014) -
miR-145 supports cancer cell survival and shows association with DDR genes, methylation pattern, and epithelial to mesenchymal transition
por: Manvati, Siddharth, et al.
Publicado: (2019) -
A replicative association study of Chromosome 6p21.3 with susceptibility to leprosy in an Indian population - 'a string hypothesis'
por: Ali, Shafat, et al.
Publicado: (2010)