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Management of jejunoileal atresias: an experience at eastern Nepal

BACKGROUND: Intestinal atresia is a common cause of neonatal intestinal obstruction, and management of this disease in limited setup of a developing country is very difficult. METHODS: This study is a retrospective study of patients with jejunoileal atresias and their postoperative outcome in a teac...

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Autores principales: Shakya, Vikal C, Agrawal, Chandra S, Shrestha, Pramod, Poudel, Prakash, Khaniya, Sudeep, Adhikary, Shailesh
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004834/
https://www.ncbi.nlm.nih.gov/pubmed/21108847
http://dx.doi.org/10.1186/1471-2482-10-35
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author Shakya, Vikal C
Agrawal, Chandra S
Shrestha, Pramod
Poudel, Prakash
Khaniya, Sudeep
Adhikary, Shailesh
author_facet Shakya, Vikal C
Agrawal, Chandra S
Shrestha, Pramod
Poudel, Prakash
Khaniya, Sudeep
Adhikary, Shailesh
author_sort Shakya, Vikal C
collection PubMed
description BACKGROUND: Intestinal atresia is a common cause of neonatal intestinal obstruction, and management of this disease in limited setup of a developing country is very difficult. METHODS: This study is a retrospective study of patients with jejunoileal atresias and their postoperative outcome in a teaching hospital in eastern Nepal over a 5-year period. RESULTS: There were 28 children (19 boys and 9 girls). 11 children (39.28%) had jejunal atresia and 17 (60.71%) had ileal atresia. Eight (28.5%) patients died, 6 were jejunal atresia (54.5%) and 2 were ileal atresia (11.7%). The most common cause of death was sepsis which occurred in 7 out of 8 cases (87.5%). The risk factors for mortality identified were leucopenia, neutropenia, delay in surgery, location of atresia and type of atresia. Jejunal atresia tended to have a higher mortality than ileal atresia, and severe types of atresia (type IIIb and IV) were more often associated with mortality than other types of atresia. The significant differences between jejunal and ileal atresia were the increased duration between presentation and surgery, longer postoperative and total hospital stay, presence of more severe atresias and an increased risk of mortality in case of jejunal atresias. CONCLUSION: The prognosis for this disease have definitely changed in the last few decades in developed countries but in our environment, problems like late presentation and diagnosis, lack of availability of good neonatal intensive care units and parenteral nutritional support still prevail.
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spelling pubmed-30048342010-12-21 Management of jejunoileal atresias: an experience at eastern Nepal Shakya, Vikal C Agrawal, Chandra S Shrestha, Pramod Poudel, Prakash Khaniya, Sudeep Adhikary, Shailesh BMC Surg Research Article BACKGROUND: Intestinal atresia is a common cause of neonatal intestinal obstruction, and management of this disease in limited setup of a developing country is very difficult. METHODS: This study is a retrospective study of patients with jejunoileal atresias and their postoperative outcome in a teaching hospital in eastern Nepal over a 5-year period. RESULTS: There were 28 children (19 boys and 9 girls). 11 children (39.28%) had jejunal atresia and 17 (60.71%) had ileal atresia. Eight (28.5%) patients died, 6 were jejunal atresia (54.5%) and 2 were ileal atresia (11.7%). The most common cause of death was sepsis which occurred in 7 out of 8 cases (87.5%). The risk factors for mortality identified were leucopenia, neutropenia, delay in surgery, location of atresia and type of atresia. Jejunal atresia tended to have a higher mortality than ileal atresia, and severe types of atresia (type IIIb and IV) were more often associated with mortality than other types of atresia. The significant differences between jejunal and ileal atresia were the increased duration between presentation and surgery, longer postoperative and total hospital stay, presence of more severe atresias and an increased risk of mortality in case of jejunal atresias. CONCLUSION: The prognosis for this disease have definitely changed in the last few decades in developed countries but in our environment, problems like late presentation and diagnosis, lack of availability of good neonatal intensive care units and parenteral nutritional support still prevail. BioMed Central 2010-11-26 /pmc/articles/PMC3004834/ /pubmed/21108847 http://dx.doi.org/10.1186/1471-2482-10-35 Text en Copyright ©2010 Shakya et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<url>http://creativecommons.org/licenses/by/2.0</url>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Shakya, Vikal C
Agrawal, Chandra S
Shrestha, Pramod
Poudel, Prakash
Khaniya, Sudeep
Adhikary, Shailesh
Management of jejunoileal atresias: an experience at eastern Nepal
title Management of jejunoileal atresias: an experience at eastern Nepal
title_full Management of jejunoileal atresias: an experience at eastern Nepal
title_fullStr Management of jejunoileal atresias: an experience at eastern Nepal
title_full_unstemmed Management of jejunoileal atresias: an experience at eastern Nepal
title_short Management of jejunoileal atresias: an experience at eastern Nepal
title_sort management of jejunoileal atresias: an experience at eastern nepal
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004834/
https://www.ncbi.nlm.nih.gov/pubmed/21108847
http://dx.doi.org/10.1186/1471-2482-10-35
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