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Modifying the Substrate Specificity of Carcinoscorpius rotundicauda Serine Protease Inhibitor Domain 1 to Target Thrombin

Protease inhibitors play a decisive role in maintaining homeostasis and eliciting antimicrobial activities. Invertebrates like the horseshoe crab have developed unique modalities with serine protease inhibitors to detect and respond to microbial and host proteases. Two isoforms of an immunomodulator...

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Detalles Bibliográficos
Autores principales:	Giri, Pankaj Kumar, Tang, Xuhua, Thangamani, Saravanan, Shenoy, Rajesh T., Ding, Jeak Ling, Swaminathan, Kunchithapadam, Sivaraman, J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004852/ https://www.ncbi.nlm.nih.gov/pubmed/21188150 http://dx.doi.org/10.1371/journal.pone.0015258

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