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Reconstructed Ancestral Sequences Improve Pathogen Identification Using Resequencing DNA Microarrays
We describe the benefit of using reconstructed ancestral sequences (RAS) on resequencing microarrays for rapid pathogen identification, with Enterobacteriaceae rpoB sequences as a model. Our results demonstrate a sharp improvement of call rate and accuracy when using RASs as compared to extant seque...
Autores principales: | Berthet, Nicolas, Deletoile, Alexis, Passet, Virginie, Kennedy, Giulia C., Manuguerra, Jean-Claude, Cole, Stewart T., Brisse, Sylvain |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004854/ https://www.ncbi.nlm.nih.gov/pubmed/21187950 http://dx.doi.org/10.1371/journal.pone.0015243 |
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