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A Serum Factor Induces Insulin-Independent Translocation of GLUT4 to the Cell Surface which Is Maintained in Insulin Resistance

In response to insulin, glucose transporter GLUT4 translocates from intracellular compartments towards the plasma membrane where it enhances cellular glucose uptake. Here, we show that sera from various species contain a factor that dose-dependently induces GLUT4 translocation and glucose uptake in...

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Detalles Bibliográficos
Autores principales: Berenguer, Marion, Martinez, Laurène, Giorgetti-Peraldi, Sophie, Le Marchand-Brustel, Yannick, Govers, Roland
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004919/
https://www.ncbi.nlm.nih.gov/pubmed/21187969
http://dx.doi.org/10.1371/journal.pone.0015560