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Enhancement of Electric Field-Mediated Gene Delivery Through Pretreatment of Tumors With a Hyperosmotic Mannitol Solution
Pulsed electric fields can enhance interstitial transport of plasmid DNA (pDNA) in solid tumors. However, the extent of enhancement is still limited. To this end, effects of cellular resistance to electric field-mediated gene delivery were investigated. The investigation used two tumor cell lines (4...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005142/ https://www.ncbi.nlm.nih.gov/pubmed/20847751 http://dx.doi.org/10.1038/cgt.2010.51 |