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Rapid spectral analysis for spectral imaging
Spectral imaging requires rapid analysis of spectra associated with each pixel. A rapid algorithm has been developed that uses iterative matrix inversions to solve for the absorption spectra of a tissue using a lookup table for photon pathlength based on numerical simulations. The algorithm uses tis...
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Formato: | Texto |
Lenguaje: | English |
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Optical Society of America
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005184/ https://www.ncbi.nlm.nih.gov/pubmed/21258455 http://dx.doi.org/10.1364/BOE.1.000157 |
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author | Jacques, Steven L. Samatham, Ravikant Choudhury, Niloy |
author_facet | Jacques, Steven L. Samatham, Ravikant Choudhury, Niloy |
author_sort | Jacques, Steven L. |
collection | PubMed |
description | Spectral imaging requires rapid analysis of spectra associated with each pixel. A rapid algorithm has been developed that uses iterative matrix inversions to solve for the absorption spectra of a tissue using a lookup table for photon pathlength based on numerical simulations. The algorithm uses tissue water content as an internal standard to specify the strength of optical scattering. An experimental example is presented on the spectroscopy of portwine stain lesions. When implemented in MATLAB, the method is ~100-fold faster than using fminsearch(). |
format | Text |
id | pubmed-3005184 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Optical Society of America |
record_format | MEDLINE/PubMed |
spelling | pubmed-30051842011-01-21 Rapid spectral analysis for spectral imaging Jacques, Steven L. Samatham, Ravikant Choudhury, Niloy Biomed Opt Express Optics of Tissue and Turbid Media Spectral imaging requires rapid analysis of spectra associated with each pixel. A rapid algorithm has been developed that uses iterative matrix inversions to solve for the absorption spectra of a tissue using a lookup table for photon pathlength based on numerical simulations. The algorithm uses tissue water content as an internal standard to specify the strength of optical scattering. An experimental example is presented on the spectroscopy of portwine stain lesions. When implemented in MATLAB, the method is ~100-fold faster than using fminsearch(). Optical Society of America 2010-07-15 /pmc/articles/PMC3005184/ /pubmed/21258455 http://dx.doi.org/10.1364/BOE.1.000157 Text en ©2010 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially. |
spellingShingle | Optics of Tissue and Turbid Media Jacques, Steven L. Samatham, Ravikant Choudhury, Niloy Rapid spectral analysis for spectral imaging |
title | Rapid spectral analysis for spectral imaging |
title_full | Rapid spectral analysis for spectral imaging |
title_fullStr | Rapid spectral analysis for spectral imaging |
title_full_unstemmed | Rapid spectral analysis for spectral imaging |
title_short | Rapid spectral analysis for spectral imaging |
title_sort | rapid spectral analysis for spectral imaging |
topic | Optics of Tissue and Turbid Media |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005184/ https://www.ncbi.nlm.nih.gov/pubmed/21258455 http://dx.doi.org/10.1364/BOE.1.000157 |
work_keys_str_mv | AT jacquesstevenl rapidspectralanalysisforspectralimaging AT samathamravikant rapidspectralanalysisforspectralimaging AT choudhuryniloy rapidspectralanalysisforspectralimaging |