Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia

Chronic HTLV-I (human T cell lymphotropic virus type I) infection may cause adult T cell leukemia/lymphoma (ATL), a disease with dismal long-term prognosis. The HTLV-I transactivator, Tax, initiates ATL in transgenic mice. In this study, we demonstrate that an As(2)O(3) and IFN-α combination, known...

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Detalles Bibliográficos
Autores principales: El Hajj, Hiba, El-Sabban, Marwan, Hasegawa, Hideki, Zaatari, Ghazi, Ablain, Julien, Saab, Shahrazad T., Janin, Anne, Mahfouz, Rami, Nasr, Rihab, Kfoury, Youmna, Nicot, Christophe, Hermine, Olivier, Hall, William, de Thé, Hugues, Bazarbachi, Ali
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005222/
https://www.ncbi.nlm.nih.gov/pubmed/21135137
http://dx.doi.org/10.1084/jem.20101095

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