Conserved natural IgM antibodies mediate innate and adaptive immunity against the opportunistic fungus Pneumocystis murina

Host defense against opportunistic fungi requires coordination between innate and adaptive immunity for resolution of infection. Antibodies generated in mice vaccinated with the fungus Pneumocystis prevent growth of Pneumocystis organisms within the lungs, but the mechanisms whereby antibodies enhan...

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Autores principales: Rapaka, Rekha R., Ricks, David M., Alcorn, John F., Chen, Kong, Khader, Shabaana A., Zheng, Mingquan, Plevy, Scott, Bengtén, Eva, Kolls, Jay K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005228/
https://www.ncbi.nlm.nih.gov/pubmed/21149550
http://dx.doi.org/10.1084/jem.20100034

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