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Nutritional Status According to Sensitized Food Allergens in Children With Atopic Dermatitis
PURPOSE: Food allergies can affect the growth and nutritional status of children with atopic dermatitis (AD). This study was conducted to determine the association between the number of sensitized food allergens and the growth and nutritional status of infants and young children with AD. METHODS: We...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005320/ https://www.ncbi.nlm.nih.gov/pubmed/21217926 http://dx.doi.org/10.4168/aair.2011.3.1.53 |
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author | Cho, Ha-Na Hong, Soyoung Lee, Soo-Hyung Yum, Hye-Yung |
author_facet | Cho, Ha-Na Hong, Soyoung Lee, Soo-Hyung Yum, Hye-Yung |
author_sort | Cho, Ha-Na |
collection | PubMed |
description | PURPOSE: Food allergies can affect the growth and nutritional status of children with atopic dermatitis (AD). This study was conducted to determine the association between the number of sensitized food allergens and the growth and nutritional status of infants and young children with AD. METHODS: We studied 165 children with AD, aged 5 to 47 months, and who visited the Atopy Clinic of the Seoul Medical Center. We recorded the birth weight, time at which food weaning began, scoring of atopic dermatitis (SCORAD) index, eosinophil counts in peripheral blood, and total serum IgE and specific IgE to six major allergens (egg white, cow's milk, soybean, peanut, wheat, and fish). The height and weight for age and weight for height were converted to z-scores to evaluate their effects on growth and nutritional status. Specific IgE levels ≥0.7 kUA/L, measured via the CAP assay, were considered positive. RESULTS: As the number of sensitized food allergens increased, the mean z-scores of weight and height for age decreased (P=0.006 and 0.018, respectively). The number directly correlated with the SCORAD index (r=0.308), time at which food weaning began (r=0.332), eosinophil counts in peripheral blood (r=0.266), and total serum IgE (r=0.394). Inverse correlations were observed with the z-scores of weight for age (r=-0.358), height for age (r=-0.278), and weight for height (r=-0.224). CONCLUSIONS: A higher number of sensitized food allergens was associated with negative effects on the growth and nutritional status of infants and young children with AD. Therefore, a thorough evaluation of both growth and nutritional status, combined with adequate patient management, is crucial in pediatric AD patients presenting with numerous sensitized food allergies. |
format | Text |
id | pubmed-3005320 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease |
record_format | MEDLINE/PubMed |
spelling | pubmed-30053202011-01-08 Nutritional Status According to Sensitized Food Allergens in Children With Atopic Dermatitis Cho, Ha-Na Hong, Soyoung Lee, Soo-Hyung Yum, Hye-Yung Allergy Asthma Immunol Res Original Article PURPOSE: Food allergies can affect the growth and nutritional status of children with atopic dermatitis (AD). This study was conducted to determine the association between the number of sensitized food allergens and the growth and nutritional status of infants and young children with AD. METHODS: We studied 165 children with AD, aged 5 to 47 months, and who visited the Atopy Clinic of the Seoul Medical Center. We recorded the birth weight, time at which food weaning began, scoring of atopic dermatitis (SCORAD) index, eosinophil counts in peripheral blood, and total serum IgE and specific IgE to six major allergens (egg white, cow's milk, soybean, peanut, wheat, and fish). The height and weight for age and weight for height were converted to z-scores to evaluate their effects on growth and nutritional status. Specific IgE levels ≥0.7 kUA/L, measured via the CAP assay, were considered positive. RESULTS: As the number of sensitized food allergens increased, the mean z-scores of weight and height for age decreased (P=0.006 and 0.018, respectively). The number directly correlated with the SCORAD index (r=0.308), time at which food weaning began (r=0.332), eosinophil counts in peripheral blood (r=0.266), and total serum IgE (r=0.394). Inverse correlations were observed with the z-scores of weight for age (r=-0.358), height for age (r=-0.278), and weight for height (r=-0.224). CONCLUSIONS: A higher number of sensitized food allergens was associated with negative effects on the growth and nutritional status of infants and young children with AD. Therefore, a thorough evaluation of both growth and nutritional status, combined with adequate patient management, is crucial in pediatric AD patients presenting with numerous sensitized food allergies. The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2011-01 2010-11-23 /pmc/articles/PMC3005320/ /pubmed/21217926 http://dx.doi.org/10.4168/aair.2011.3.1.53 Text en Copyright © 2011 The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Cho, Ha-Na Hong, Soyoung Lee, Soo-Hyung Yum, Hye-Yung Nutritional Status According to Sensitized Food Allergens in Children With Atopic Dermatitis |
title | Nutritional Status According to Sensitized Food Allergens in Children With Atopic Dermatitis |
title_full | Nutritional Status According to Sensitized Food Allergens in Children With Atopic Dermatitis |
title_fullStr | Nutritional Status According to Sensitized Food Allergens in Children With Atopic Dermatitis |
title_full_unstemmed | Nutritional Status According to Sensitized Food Allergens in Children With Atopic Dermatitis |
title_short | Nutritional Status According to Sensitized Food Allergens in Children With Atopic Dermatitis |
title_sort | nutritional status according to sensitized food allergens in children with atopic dermatitis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005320/ https://www.ncbi.nlm.nih.gov/pubmed/21217926 http://dx.doi.org/10.4168/aair.2011.3.1.53 |
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