Constitutional Growth Delay Pattern of Growth in Velo−Cardio−Facial Syndrome: Longitudinal follow up and final height of two cases

We report two patients with velo−cardio−facial syndrome (VCFS) who were admitted to our pediatric endocrinology clinic because of short stature and followed longitudinally until attainment of final height. Both patients followed a growth pattern consistent with constitutional delay of puberty with n...

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Autores principales: Turan, Serap, Özdemir, Nihal, Güran, Tülay, Akalın, Figen, Akçay, Teoman, Ayabakan, Canan, Yılmaz, Yüksel, Bereket, Abdullah
Formato: Texto
Lenguaje:English
Publicado: Galenos Publishing 2008
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005635/
https://www.ncbi.nlm.nih.gov/pubmed/21318064
http://dx.doi.org/10.4008/jcrpe.v1i1.13
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author Turan, Serap
Özdemir, Nihal
Güran, Tülay
Akalın, Figen
Akçay, Teoman
Ayabakan, Canan
Yılmaz, Yüksel
Bereket, Abdullah
author_facet Turan, Serap
Özdemir, Nihal
Güran, Tülay
Akalın, Figen
Akçay, Teoman
Ayabakan, Canan
Yılmaz, Yüksel
Bereket, Abdullah
author_sort Turan, Serap
collection PubMed
description We report two patients with velo−cardio−facial syndrome (VCFS) who were admitted to our pediatric endocrinology clinic because of short stature and followed longitudinally until attainment of final height. Both patients followed a growth pattern consistent with constitutional delay of puberty with normal and near normal final height. Case 2 also had partial growth hormone (GH) deficiency and severe short stature (height SDS −3.4 SDS), but showed spontaneous catch−up and ended up with a final height of −2 SDS. These cases suggest that short stature in children with VCFS is due to a pattern of growth similar to that observed in constitutional delay of growth and puberty. Conflict of interest:None declared.
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spelling pubmed-30056352011-01-27 Constitutional Growth Delay Pattern of Growth in Velo−Cardio−Facial Syndrome: Longitudinal follow up and final height of two cases Turan, Serap Özdemir, Nihal Güran, Tülay Akalın, Figen Akçay, Teoman Ayabakan, Canan Yılmaz, Yüksel Bereket, Abdullah J Clin Res Pediatr Endocrinol Case Reports We report two patients with velo−cardio−facial syndrome (VCFS) who were admitted to our pediatric endocrinology clinic because of short stature and followed longitudinally until attainment of final height. Both patients followed a growth pattern consistent with constitutional delay of puberty with normal and near normal final height. Case 2 also had partial growth hormone (GH) deficiency and severe short stature (height SDS −3.4 SDS), but showed spontaneous catch−up and ended up with a final height of −2 SDS. These cases suggest that short stature in children with VCFS is due to a pattern of growth similar to that observed in constitutional delay of growth and puberty. Conflict of interest:None declared. Galenos Publishing 2008-09 2008-08-07 /pmc/articles/PMC3005635/ /pubmed/21318064 http://dx.doi.org/10.4008/jcrpe.v1i1.13 Text en © Journal of Clinical Research in Pediatric Endocrinology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Turan, Serap
Özdemir, Nihal
Güran, Tülay
Akalın, Figen
Akçay, Teoman
Ayabakan, Canan
Yılmaz, Yüksel
Bereket, Abdullah
Constitutional Growth Delay Pattern of Growth in Velo−Cardio−Facial Syndrome: Longitudinal follow up and final height of two cases
title Constitutional Growth Delay Pattern of Growth in Velo−Cardio−Facial Syndrome: Longitudinal follow up and final height of two cases
title_full Constitutional Growth Delay Pattern of Growth in Velo−Cardio−Facial Syndrome: Longitudinal follow up and final height of two cases
title_fullStr Constitutional Growth Delay Pattern of Growth in Velo−Cardio−Facial Syndrome: Longitudinal follow up and final height of two cases
title_full_unstemmed Constitutional Growth Delay Pattern of Growth in Velo−Cardio−Facial Syndrome: Longitudinal follow up and final height of two cases
title_short Constitutional Growth Delay Pattern of Growth in Velo−Cardio−Facial Syndrome: Longitudinal follow up and final height of two cases
title_sort constitutional growth delay pattern of growth in velo−cardio−facial syndrome: longitudinal follow up and final height of two cases
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005635/
https://www.ncbi.nlm.nih.gov/pubmed/21318064
http://dx.doi.org/10.4008/jcrpe.v1i1.13
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