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Neonatal Diabetes Mellitus Accompanied by Diabetic Ketoacidosis and Mimicking Neonatal Sepsis: A Case Report
Neonatal diabetes mellitus (DM) develops within the first six weeks of life with basic findings including dehydration, hyperglycaemia, and mild or no ketonemia/ketonuria. It can be either transient or permanent. Here, we report a case of a one−month−old infant with permanent neonatal diabetes, due t...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Galenos Publishing
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005678/ https://www.ncbi.nlm.nih.gov/pubmed/21274328 http://dx.doi.org/10.4274/jcrpe.v2i3.131 |
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author | Abacı, Ayhan Razi, Cem Hasan Özdemir, Osman Hızlı, Samil Kıslal, Fatih Argas, Pınar Işık Kabakuş, Nimet |
author_facet | Abacı, Ayhan Razi, Cem Hasan Özdemir, Osman Hızlı, Samil Kıslal, Fatih Argas, Pınar Işık Kabakuş, Nimet |
author_sort | Abacı, Ayhan |
collection | PubMed |
description | Neonatal diabetes mellitus (DM) develops within the first six weeks of life with basic findings including dehydration, hyperglycaemia, and mild or no ketonemia/ketonuria. It can be either transient or permanent. Here, we report a case of a one−month−old infant with permanent neonatal diabetes, due to pancreatic hypoplasia, accompanied by diabetic ketoacidosis (DKA). The hyperglycaemia and ketoacidosis resolved by the 14(th) hour of treatment, consisting of IV insulin and rehydration. Subsequently, insulin treatment was continued with neutral protamine hagedorn (NPH) insulin. Breastfeeding was started and was continued at intervals of three hours. Following initiation of breastfeeding, the stools became watery, loose, yellow−green in color, and frequent (8−10 times a day). They contained no blood or mucus. Replacement of pancreatic enzymes resulted in decreased stool frequency. Neonatal DM due to pancreatic hypoplasia and associated with DKA may mimic sepsis and should be kept in mind in all newborns who present with fever, dehydration, and weight loss. Conflict of interest:None declared. |
format | Text |
id | pubmed-3005678 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Galenos Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-30056782011-01-27 Neonatal Diabetes Mellitus Accompanied by Diabetic Ketoacidosis and Mimicking Neonatal Sepsis: A Case Report Abacı, Ayhan Razi, Cem Hasan Özdemir, Osman Hızlı, Samil Kıslal, Fatih Argas, Pınar Işık Kabakuş, Nimet J Clin Res Pediatr Endocrinol Case Reports Neonatal diabetes mellitus (DM) develops within the first six weeks of life with basic findings including dehydration, hyperglycaemia, and mild or no ketonemia/ketonuria. It can be either transient or permanent. Here, we report a case of a one−month−old infant with permanent neonatal diabetes, due to pancreatic hypoplasia, accompanied by diabetic ketoacidosis (DKA). The hyperglycaemia and ketoacidosis resolved by the 14(th) hour of treatment, consisting of IV insulin and rehydration. Subsequently, insulin treatment was continued with neutral protamine hagedorn (NPH) insulin. Breastfeeding was started and was continued at intervals of three hours. Following initiation of breastfeeding, the stools became watery, loose, yellow−green in color, and frequent (8−10 times a day). They contained no blood or mucus. Replacement of pancreatic enzymes resulted in decreased stool frequency. Neonatal DM due to pancreatic hypoplasia and associated with DKA may mimic sepsis and should be kept in mind in all newborns who present with fever, dehydration, and weight loss. Conflict of interest:None declared. Galenos Publishing 2010-09 2010-08-08 /pmc/articles/PMC3005678/ /pubmed/21274328 http://dx.doi.org/10.4274/jcrpe.v2i3.131 Text en © Journal of Clinical Research in Pediatric Endocrinology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Reports Abacı, Ayhan Razi, Cem Hasan Özdemir, Osman Hızlı, Samil Kıslal, Fatih Argas, Pınar Işık Kabakuş, Nimet Neonatal Diabetes Mellitus Accompanied by Diabetic Ketoacidosis and Mimicking Neonatal Sepsis: A Case Report |
title | Neonatal Diabetes Mellitus Accompanied by Diabetic Ketoacidosis and Mimicking Neonatal Sepsis: A Case Report |
title_full | Neonatal Diabetes Mellitus Accompanied by Diabetic Ketoacidosis and Mimicking Neonatal Sepsis: A Case Report |
title_fullStr | Neonatal Diabetes Mellitus Accompanied by Diabetic Ketoacidosis and Mimicking Neonatal Sepsis: A Case Report |
title_full_unstemmed | Neonatal Diabetes Mellitus Accompanied by Diabetic Ketoacidosis and Mimicking Neonatal Sepsis: A Case Report |
title_short | Neonatal Diabetes Mellitus Accompanied by Diabetic Ketoacidosis and Mimicking Neonatal Sepsis: A Case Report |
title_sort | neonatal diabetes mellitus accompanied by diabetic ketoacidosis and mimicking neonatal sepsis: a case report |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005678/ https://www.ncbi.nlm.nih.gov/pubmed/21274328 http://dx.doi.org/10.4274/jcrpe.v2i3.131 |
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