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Probing the anticancer mechanism of prospective herbal drug Withaferin A on mammals: a case study on human and bovine proteasomes

BACKGROUND: The UPP (ubiquitin proteasome pathway) is the major proteolytic system in the cytosol and nucleus of all eukaryotic cells which regulates cellular events, including mitotis, differentiation, signal transduction, apoptosis, and inflammation. UPP controls activation of the transcriptional...

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Detalles Bibliográficos
Autores principales: Grover, Abhinav, Shandilya, Ashutosh, Bisaria, Virendra S, Sundar, Durai
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005937/
https://www.ncbi.nlm.nih.gov/pubmed/21143798
http://dx.doi.org/10.1186/1471-2164-11-S4-S15

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