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A novel insight into aging: are there pluripotent very small embryonic-like stem cells (VSELs) in adult tissues overtime depleted in an Igf-1-dependent manner?

Tissue and organ rejuvenation and senescence/aging are closely related to the function of stem cells. Recently, we demonstrated that a population of pluripotent Oct-4(+) SSEA-1(+)Sca-1(+)Lin(-)CD45(-) very small embryonic-like stem cells (VSELs) resides in the adult murine bone marrow (BM) and other...

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Detalles Bibliográficos
Autores principales:	Ratajczak, Mariusz Z., Shin, Dong-Myung, Ratajczak, Janina, Kucia, Magda, Bartke, Andrzej
Formato:	Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2010
Materias:	Research Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006029/ https://www.ncbi.nlm.nih.gov/pubmed/21084728

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