Cargando…

Stochastic Competition between Mechanistically Independent Slippage and Death Pathways Determines Cell Fate during Mitotic Arrest

Variability in cell-to-cell behavior within clonal populations can be attributed to the inherent stochasticity of biochemical reactions. Most single-cell studies have examined variation in behavior due to randomness in gene transcription. Here we investigate the mechanism of cell fate choice and the...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Hsiao-Chun, Mitchison, Timothy J., Shi, Jue
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006339/
https://www.ncbi.nlm.nih.gov/pubmed/21203573
http://dx.doi.org/10.1371/journal.pone.0015724