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Stochastic Competition between Mechanistically Independent Slippage and Death Pathways Determines Cell Fate during Mitotic Arrest
Variability in cell-to-cell behavior within clonal populations can be attributed to the inherent stochasticity of biochemical reactions. Most single-cell studies have examined variation in behavior due to randomness in gene transcription. Here we investigate the mechanism of cell fate choice and the...
Autores principales: | Huang, Hsiao-Chun, Mitchison, Timothy J., Shi, Jue |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006339/ https://www.ncbi.nlm.nih.gov/pubmed/21203573 http://dx.doi.org/10.1371/journal.pone.0015724 |
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