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Prox1 Regulates the Notch1-Mediated Inhibition of Neurogenesis

Activation of Notch1 signaling in neural progenitor cells (NPCs) induces self-renewal and inhibits neurogenesis. Upon neuronal differentiation, NPCs overcome this inhibition, express proneural genes to induce Notch ligands, and activate Notch1 in neighboring NPCs. The molecular mechanism that coordi...

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Detalles Bibliográficos
Autores principales:	Kaltezioti, Valeria, Kouroupi, Georgia, Oikonomaki, Maria, Mantouvalou, Evangelia, Stergiopoulos, Athanasios, Charonis, Aristidis, Rohrer, Hermann, Matsas, Rebecca, Politis, Panagiotis K.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006385/ https://www.ncbi.nlm.nih.gov/pubmed/21203589 http://dx.doi.org/10.1371/journal.pbio.1000565

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