Inhibitors of Foot and Mouth Disease Virus Targeting a Novel Pocket of the RNA-Dependent RNA Polymerase

BACKGROUND: Foot-and-Mouth Disease Virus (FMDV) is a picornavirus that infects cloven-hoofed animals and leads to severe losses in livestock production. In the case of an FMD outbreak, emergency vaccination requires at least 7 days to trigger an effective immune response. There are currently no appr...

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Detalles Bibliográficos
Autores principales: Durk, Ryan C., Singh, Kamalendra, Cornelison, Ceili A., Rai, Devendra K., Matzek, Kayla B., Leslie, Maxwell D., Schafer, Elizabeth, Marchand, Bruno, Adedeji, Adeyemi, Michailidis, Eleftherios, Dorst, Christopher A., Moran, Jennifer, Pautler, Christie, Rodriguez, Luis L., McIntosh, Mark A., Rieder, Elizabeth, Sarafianos, Stefan G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006429/
https://www.ncbi.nlm.nih.gov/pubmed/21203539
http://dx.doi.org/10.1371/journal.pone.0015049

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