Conformation and absolute configuration of (1S,2S)-2-(phenyl­selan­yl)cyclo­hexyl (R)-2-meth­oxy-2-(1-naphth­yl)propionate

The relative and absolute configurations of the title compound, C(26)H(28)O(3)Se, were assigned from the known configuration of (R)-(−)-2-meth­oxy-2-(1-naphth­yl)propionic acid used as starting material, and by examination of the Bijvoet (Friedel) pairs, using the anomalous dispersion data collected...

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Detalles Bibliográficos
Autores principales: Murakami, Satoshi, Kato, Akane, Katagiri, Hiroshi, Matsumoto, Takatoshi, Kijima, Tatsuro
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006699/
https://www.ncbi.nlm.nih.gov/pubmed/21587902
http://dx.doi.org/10.1107/S1600536810022233
Descripción
Sumario:The relative and absolute configurations of the title compound, C(26)H(28)O(3)Se, were assigned from the known configuration of (R)-(−)-2-meth­oxy-2-(1-naphth­yl)propionic acid used as starting material, and by examination of the Bijvoet (Friedel) pairs, using the anomalous dispersion data collected with Mo Kα radiation at low temperature. The geometry around the carbonyl group exists in the syn conformation, as reflected in torsion angles involving this group, and the stability of the structure is affected by weak bifurcated intra­molecular C—H⋯O hydrogen bonds.

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