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6-(4-Amino­phen­yl)-2-eth­oxy-4-(2-thien­yl)nicotinonitrile

In the title nicotinonitrile derivative, C(18)H(15)N(3)OS, the central pyridyl ring makes dihedral angles of 25.22 (10) and 24.80 (16)° with the 4-amino­phenyl and thio­phene rings, respectively. The thio­phene ring is disordered over two orientations by rotation around the C(thio­phene)—C(pyridine)...

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Detalles Bibliográficos
Autores principales: Fun, Hoong-Kun, Chantrapromma, Suchada, Kobkeatthawin, Thawanrat, Padaki, Mahesh, Isloor, Arun M.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006713/
https://www.ncbi.nlm.nih.gov/pubmed/21588020
http://dx.doi.org/10.1107/S160053681002369X
Descripción
Sumario:In the title nicotinonitrile derivative, C(18)H(15)N(3)OS, the central pyridyl ring makes dihedral angles of 25.22 (10) and 24.80 (16)° with the 4-amino­phenyl and thio­phene rings, respectively. The thio­phene ring is disordered over two orientations by rotation around the C(thio­phene)—C(pyridine) bond; the occupancies are 0.858 (2) and 0.142 (2). The eth­oxy group is slightly twisted from the attached pyridyl ring [C—O—C—C torsion angle = 171.13 (16)°]. In the crystal structure, mol­ecules are linked by N—H⋯N hydrogen bonds into chains along [010]. These chains are stacked along the a axis. C—H⋯π weak inter­actions involving the thio­phene ring are observed.