6-(4-Amino­phen­yl)-2-eth­oxy-4-(2-thien­yl)nicotinonitrile

In the title nicotinonitrile derivative, C(18)H(15)N(3)OS, the central pyridyl ring makes dihedral angles of 25.22 (10) and 24.80 (16)° with the 4-amino­phenyl and thio­phene rings, respectively. The thio­phene ring is disordered over two orientations by rotation around the C(thio­phene)—C(pyridine)...

Descripción completa

Detalles Bibliográficos
Autores principales: Fun, Hoong-Kun, Chantrapromma, Suchada, Kobkeatthawin, Thawanrat, Padaki, Mahesh, Isloor, Arun M.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006713/
https://www.ncbi.nlm.nih.gov/pubmed/21588020
http://dx.doi.org/10.1107/S160053681002369X
_version_ 1782194204020047872
author Fun, Hoong-Kun
Chantrapromma, Suchada
Kobkeatthawin, Thawanrat
Padaki, Mahesh
Isloor, Arun M.
author_facet Fun, Hoong-Kun
Chantrapromma, Suchada
Kobkeatthawin, Thawanrat
Padaki, Mahesh
Isloor, Arun M.
author_sort Fun, Hoong-Kun
collection PubMed
description In the title nicotinonitrile derivative, C(18)H(15)N(3)OS, the central pyridyl ring makes dihedral angles of 25.22 (10) and 24.80 (16)° with the 4-amino­phenyl and thio­phene rings, respectively. The thio­phene ring is disordered over two orientations by rotation around the C(thio­phene)—C(pyridine) bond; the occupancies are 0.858 (2) and 0.142 (2). The eth­oxy group is slightly twisted from the attached pyridyl ring [C—O—C—C torsion angle = 171.13 (16)°]. In the crystal structure, mol­ecules are linked by N—H⋯N hydrogen bonds into chains along [010]. These chains are stacked along the a axis. C—H⋯π weak inter­actions involving the thio­phene ring are observed.
format Text
id pubmed-3006713
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-30067132010-12-30 6-(4-Amino­phen­yl)-2-eth­oxy-4-(2-thien­yl)nicotinonitrile Fun, Hoong-Kun Chantrapromma, Suchada Kobkeatthawin, Thawanrat Padaki, Mahesh Isloor, Arun M. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title nicotinonitrile derivative, C(18)H(15)N(3)OS, the central pyridyl ring makes dihedral angles of 25.22 (10) and 24.80 (16)° with the 4-amino­phenyl and thio­phene rings, respectively. The thio­phene ring is disordered over two orientations by rotation around the C(thio­phene)—C(pyridine) bond; the occupancies are 0.858 (2) and 0.142 (2). The eth­oxy group is slightly twisted from the attached pyridyl ring [C—O—C—C torsion angle = 171.13 (16)°]. In the crystal structure, mol­ecules are linked by N—H⋯N hydrogen bonds into chains along [010]. These chains are stacked along the a axis. C—H⋯π weak inter­actions involving the thio­phene ring are observed. International Union of Crystallography 2010-06-26 /pmc/articles/PMC3006713/ /pubmed/21588020 http://dx.doi.org/10.1107/S160053681002369X Text en © Fun et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Fun, Hoong-Kun
Chantrapromma, Suchada
Kobkeatthawin, Thawanrat
Padaki, Mahesh
Isloor, Arun M.
6-(4-Amino­phen­yl)-2-eth­oxy-4-(2-thien­yl)nicotinonitrile
title 6-(4-Amino­phen­yl)-2-eth­oxy-4-(2-thien­yl)nicotinonitrile
title_full 6-(4-Amino­phen­yl)-2-eth­oxy-4-(2-thien­yl)nicotinonitrile
title_fullStr 6-(4-Amino­phen­yl)-2-eth­oxy-4-(2-thien­yl)nicotinonitrile
title_full_unstemmed 6-(4-Amino­phen­yl)-2-eth­oxy-4-(2-thien­yl)nicotinonitrile
title_short 6-(4-Amino­phen­yl)-2-eth­oxy-4-(2-thien­yl)nicotinonitrile
title_sort 6-(4-amino­phen­yl)-2-eth­oxy-4-(2-thien­yl)nicotinonitrile
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006713/
https://www.ncbi.nlm.nih.gov/pubmed/21588020
http://dx.doi.org/10.1107/S160053681002369X
work_keys_str_mv AT funhoongkun 64aminophenyl2ethoxy42thienylnicotinonitrile
AT chantraprommasuchada 64aminophenyl2ethoxy42thienylnicotinonitrile
AT kobkeatthawinthawanrat 64aminophenyl2ethoxy42thienylnicotinonitrile
AT padakimahesh 64aminophenyl2ethoxy42thienylnicotinonitrile
AT isloorarunm 64aminophenyl2ethoxy42thienylnicotinonitrile

Ejemplares similares