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Ethyl 1-(2-hy­droxy­eth­yl)-2-phenyl-1H-benzimidazole-5-carboxyl­ate

There are two mol­ecules in the asymmetric unit of the title compound, C(18)H(18)N(2)O(3). In each one, the benzimidazole ring system is essentially planar, with maximum deviations of 0.027 (1) and 0.032 (1)Å, and makes dihedral angles of 38.64 (6) and 41.48 (6)°, respectively, with the attached ben...

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Autores principales: Hamzah, Nurasyikin, Abd. Hamid, Shafida, Abdul Rahim, Aisyah Saad, Rosli, Mohd Mustaqim, Fun, Hoong-Kun
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006730/
https://www.ncbi.nlm.nih.gov/pubmed/21588031
http://dx.doi.org/10.1107/S1600536810023639
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author Hamzah, Nurasyikin
Abd. Hamid, Shafida
Abdul Rahim, Aisyah Saad
Rosli, Mohd Mustaqim
Fun, Hoong-Kun
author_facet Hamzah, Nurasyikin
Abd. Hamid, Shafida
Abdul Rahim, Aisyah Saad
Rosli, Mohd Mustaqim
Fun, Hoong-Kun
author_sort Hamzah, Nurasyikin
collection PubMed
description There are two mol­ecules in the asymmetric unit of the title compound, C(18)H(18)N(2)O(3). In each one, the benzimidazole ring system is essentially planar, with maximum deviations of 0.027 (1) and 0.032 (1)Å, and makes dihedral angles of 38.64 (6) and 41.48 (6)°, respectively, with the attached benzene rings. An intra­molecular C—H⋯O hydrogen bond is observed in each mol­ecule. The two independent mol­ecules are connected into a dimer by two inter­molecular O—H⋯N hydrogen bonds. In the crystal, mol­ecules form a two-dimensional layers parallel to (012) via weak inter­molecular C—H⋯O hydrogen bonds. In addition, weak π-π stacking inter­actions are observed with centroid–centroid distances of 3.5244 (12) and 3.6189 (12) Å.
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spelling pubmed-30067302010-12-30 Ethyl 1-(2-hy­droxy­eth­yl)-2-phenyl-1H-benzimidazole-5-carboxyl­ate Hamzah, Nurasyikin Abd. Hamid, Shafida Abdul Rahim, Aisyah Saad Rosli, Mohd Mustaqim Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers There are two mol­ecules in the asymmetric unit of the title compound, C(18)H(18)N(2)O(3). In each one, the benzimidazole ring system is essentially planar, with maximum deviations of 0.027 (1) and 0.032 (1)Å, and makes dihedral angles of 38.64 (6) and 41.48 (6)°, respectively, with the attached benzene rings. An intra­molecular C—H⋯O hydrogen bond is observed in each mol­ecule. The two independent mol­ecules are connected into a dimer by two inter­molecular O—H⋯N hydrogen bonds. In the crystal, mol­ecules form a two-dimensional layers parallel to (012) via weak inter­molecular C—H⋯O hydrogen bonds. In addition, weak π-π stacking inter­actions are observed with centroid–centroid distances of 3.5244 (12) and 3.6189 (12) Å. International Union of Crystallography 2010-06-26 /pmc/articles/PMC3006730/ /pubmed/21588031 http://dx.doi.org/10.1107/S1600536810023639 Text en © Hamzah et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Hamzah, Nurasyikin
Abd. Hamid, Shafida
Abdul Rahim, Aisyah Saad
Rosli, Mohd Mustaqim
Fun, Hoong-Kun
Ethyl 1-(2-hy­droxy­eth­yl)-2-phenyl-1H-benzimidazole-5-carboxyl­ate
title Ethyl 1-(2-hy­droxy­eth­yl)-2-phenyl-1H-benzimidazole-5-carboxyl­ate
title_full Ethyl 1-(2-hy­droxy­eth­yl)-2-phenyl-1H-benzimidazole-5-carboxyl­ate
title_fullStr Ethyl 1-(2-hy­droxy­eth­yl)-2-phenyl-1H-benzimidazole-5-carboxyl­ate
title_full_unstemmed Ethyl 1-(2-hy­droxy­eth­yl)-2-phenyl-1H-benzimidazole-5-carboxyl­ate
title_short Ethyl 1-(2-hy­droxy­eth­yl)-2-phenyl-1H-benzimidazole-5-carboxyl­ate
title_sort ethyl 1-(2-hy­droxy­eth­yl)-2-phenyl-1h-benzimidazole-5-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006730/
https://www.ncbi.nlm.nih.gov/pubmed/21588031
http://dx.doi.org/10.1107/S1600536810023639
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