N-{2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]eth­yl}pyridin-2-amine monohydrate

In the title compound, C(18)H(24)N(4)O·H(2)O, the piperizine ring adopts a chair conformation and the dihedral angle between the phenyl and pyridine rings is 39.9 (3)°. The comformations of the attachment of the anisole and N-ethyl­pyridin-2-amine groups to the piperazine ring are +anti­periplanar....

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Detalles Bibliográficos
Autores principales: Jiang, Quan-Fu, Lu, Chun-Xiong
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006790/
https://www.ncbi.nlm.nih.gov/pubmed/21587944
http://dx.doi.org/10.1107/S1600536810022816
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author Jiang, Quan-Fu
Lu, Chun-Xiong
author_facet Jiang, Quan-Fu
Lu, Chun-Xiong
author_sort Jiang, Quan-Fu
collection PubMed
description In the title compound, C(18)H(24)N(4)O·H(2)O, the piperizine ring adopts a chair conformation and the dihedral angle between the phenyl and pyridine rings is 39.9 (3)°. The comformations of the attachment of the anisole and N-ethyl­pyridin-2-amine groups to the piperazine ring are +anti­periplanar. An intra­molecular C—H⋯O inter­action occurs. In the crystal, the water mol­ecule links the mol­ecules into chains through O—H⋯N hydrogen bonds. Weak N—H⋯O, C—H⋯N and C—H⋯O inter­actions further stabilize the crystal structure.
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spelling pubmed-30067902010-12-30 N-{2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]eth­yl}pyridin-2-amine monohydrate Jiang, Quan-Fu Lu, Chun-Xiong Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(18)H(24)N(4)O·H(2)O, the piperizine ring adopts a chair conformation and the dihedral angle between the phenyl and pyridine rings is 39.9 (3)°. The comformations of the attachment of the anisole and N-ethyl­pyridin-2-amine groups to the piperazine ring are +anti­periplanar. An intra­molecular C—H⋯O inter­action occurs. In the crystal, the water mol­ecule links the mol­ecules into chains through O—H⋯N hydrogen bonds. Weak N—H⋯O, C—H⋯N and C—H⋯O inter­actions further stabilize the crystal structure. International Union of Crystallography 2010-06-23 /pmc/articles/PMC3006790/ /pubmed/21587944 http://dx.doi.org/10.1107/S1600536810022816 Text en © Jiang and Lu 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Jiang, Quan-Fu
Lu, Chun-Xiong
N-{2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]eth­yl}pyridin-2-amine monohydrate
title N-{2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]eth­yl}pyridin-2-amine monohydrate
title_full N-{2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]eth­yl}pyridin-2-amine monohydrate
title_fullStr N-{2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]eth­yl}pyridin-2-amine monohydrate
title_full_unstemmed N-{2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]eth­yl}pyridin-2-amine monohydrate
title_short N-{2-[4-(2-Meth­oxy­phen­yl)piperazin-1-yl]eth­yl}pyridin-2-amine monohydrate
title_sort n-{2-[4-(2-meth­oxy­phen­yl)piperazin-1-yl]eth­yl}pyridin-2-amine monohydrate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006790/
https://www.ncbi.nlm.nih.gov/pubmed/21587944
http://dx.doi.org/10.1107/S1600536810022816
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AT luchunxiong n242methoxyphenylpiperazin1ylethylpyridin2aminemonohydrate

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