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2-(6-Bromo-3-pyridyl)-8-methylimidazo[1,2-a]pyrazine
The structure of the title compound, C(12)H(9)BrN(4), prepared by the reaction of 2-bromo-1-(6-bromo-3-pyridyl)ethanone with 2-amino-3-methylpyrazine indicates that the compound with the bromopyridyl substituent at position 2 of the imidazopyrazine fused-ring system represents the major product o...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006940/ https://www.ncbi.nlm.nih.gov/pubmed/21587940 http://dx.doi.org/10.1107/S1600536810022993 |
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author | Huang, Buwen Rui, Eugene Wythes, Martin Kung, Pei-Pei Moore, Curtis Rheingold, Arnold L. Yanovsky, Alex |
author_facet | Huang, Buwen Rui, Eugene Wythes, Martin Kung, Pei-Pei Moore, Curtis Rheingold, Arnold L. Yanovsky, Alex |
author_sort | Huang, Buwen |
collection | PubMed |
description | The structure of the title compound, C(12)H(9)BrN(4), prepared by the reaction of 2-bromo-1-(6-bromo-3-pyridyl)ethanone with 2-amino-3-methylpyrazine indicates that the compound with the bromopyridyl substituent at position 2 of the imidazopyrazine fused-ring system represents the major product of this reaction. The plane of the pyridine ring forms a dihedral angle of 16.2 (2)° with the essentially planar (r.m.s. deviation = 0.006 Å) imidazopyrazine system. In the crystal, molecules are linked by weak C—H⋯N interactions. |
format | Text |
id | pubmed-3006940 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-30069402010-12-30 2-(6-Bromo-3-pyridyl)-8-methylimidazo[1,2-a]pyrazine Huang, Buwen Rui, Eugene Wythes, Martin Kung, Pei-Pei Moore, Curtis Rheingold, Arnold L. Yanovsky, Alex Acta Crystallogr Sect E Struct Rep Online Organic Papers The structure of the title compound, C(12)H(9)BrN(4), prepared by the reaction of 2-bromo-1-(6-bromo-3-pyridyl)ethanone with 2-amino-3-methylpyrazine indicates that the compound with the bromopyridyl substituent at position 2 of the imidazopyrazine fused-ring system represents the major product of this reaction. The plane of the pyridine ring forms a dihedral angle of 16.2 (2)° with the essentially planar (r.m.s. deviation = 0.006 Å) imidazopyrazine system. In the crystal, molecules are linked by weak C—H⋯N interactions. International Union of Crystallography 2010-06-23 /pmc/articles/PMC3006940/ /pubmed/21587940 http://dx.doi.org/10.1107/S1600536810022993 Text en © Huang et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Huang, Buwen Rui, Eugene Wythes, Martin Kung, Pei-Pei Moore, Curtis Rheingold, Arnold L. Yanovsky, Alex 2-(6-Bromo-3-pyridyl)-8-methylimidazo[1,2-a]pyrazine |
title | 2-(6-Bromo-3-pyridyl)-8-methylimidazo[1,2-a]pyrazine |
title_full | 2-(6-Bromo-3-pyridyl)-8-methylimidazo[1,2-a]pyrazine |
title_fullStr | 2-(6-Bromo-3-pyridyl)-8-methylimidazo[1,2-a]pyrazine |
title_full_unstemmed | 2-(6-Bromo-3-pyridyl)-8-methylimidazo[1,2-a]pyrazine |
title_short | 2-(6-Bromo-3-pyridyl)-8-methylimidazo[1,2-a]pyrazine |
title_sort | 2-(6-bromo-3-pyridyl)-8-methylimidazo[1,2-a]pyrazine |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006940/ https://www.ncbi.nlm.nih.gov/pubmed/21587940 http://dx.doi.org/10.1107/S1600536810022993 |
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