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(4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfonyl}-2-oxo-1,3-oxazolidine-3-carboxamide
The title compound, C(21)H(21)N(3)O(7)S, contains an oxazolidinone ring and a sulfonamide group, both characteristic for biologically and pharrmaceutically active compounds. Both stereogenic centres reveal an S absolute configuration. The two oxazolidinone rings are in an envelope conformation with...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007004/ https://www.ncbi.nlm.nih.gov/pubmed/21587844 http://dx.doi.org/10.1107/S1600536810020866 |
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author | Berredjem, Malika Allaoui, Assia Direm, Amani Aouf, Noureddine Benali-Cherif, Nourredine |
author_facet | Berredjem, Malika Allaoui, Assia Direm, Amani Aouf, Noureddine Benali-Cherif, Nourredine |
author_sort | Berredjem, Malika |
collection | PubMed |
description | The title compound, C(21)H(21)N(3)O(7)S, contains an oxazolidinone ring and a sulfonamide group, both characteristic for biologically and pharrmaceutically active compounds. Both stereogenic centres reveal an S absolute configuration. The two oxazolidinone rings are in an envelope conformation with the methylene carbon flap atoms deviating by 0.428 (1) and 0.364 (2) Å from the best least-square planes formed by the four other ring atoms. An intramolecular N—H⋯O hydrogen bond contributes to the folded conformation of the molecule. In the crystal, weak intermolecular C—H⋯O interactions connect the molecules into helices along the the twofold screw axes. |
format | Text |
id | pubmed-3007004 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-30070042010-12-30 (4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfonyl}-2-oxo-1,3-oxazolidine-3-carboxamide Berredjem, Malika Allaoui, Assia Direm, Amani Aouf, Noureddine Benali-Cherif, Nourredine Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(21)H(21)N(3)O(7)S, contains an oxazolidinone ring and a sulfonamide group, both characteristic for biologically and pharrmaceutically active compounds. Both stereogenic centres reveal an S absolute configuration. The two oxazolidinone rings are in an envelope conformation with the methylene carbon flap atoms deviating by 0.428 (1) and 0.364 (2) Å from the best least-square planes formed by the four other ring atoms. An intramolecular N—H⋯O hydrogen bond contributes to the folded conformation of the molecule. In the crystal, weak intermolecular C—H⋯O interactions connect the molecules into helices along the the twofold screw axes. International Union of Crystallography 2010-06-09 /pmc/articles/PMC3007004/ /pubmed/21587844 http://dx.doi.org/10.1107/S1600536810020866 Text en © Berredjem et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Berredjem, Malika Allaoui, Assia Direm, Amani Aouf, Noureddine Benali-Cherif, Nourredine (4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfonyl}-2-oxo-1,3-oxazolidine-3-carboxamide |
title | (4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfonyl}-2-oxo-1,3-oxazolidine-3-carboxamide |
title_full | (4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfonyl}-2-oxo-1,3-oxazolidine-3-carboxamide |
title_fullStr | (4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfonyl}-2-oxo-1,3-oxazolidine-3-carboxamide |
title_full_unstemmed | (4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfonyl}-2-oxo-1,3-oxazolidine-3-carboxamide |
title_short | (4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfonyl}-2-oxo-1,3-oxazolidine-3-carboxamide |
title_sort | (4s)-4-benzyl-n-{[(4s)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfonyl}-2-oxo-1,3-oxazolidine-3-carboxamide |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007004/ https://www.ncbi.nlm.nih.gov/pubmed/21587844 http://dx.doi.org/10.1107/S1600536810020866 |
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