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(4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfon­yl}-2-oxo-1,3-oxazolidine-3-carboxamide

The title compound, C(21)H(21)N(3)O(7)S, contains an oxazolidinone ring and a sulfonamide group, both characteristic for biologically and pharrmaceutically active compounds. Both stereogenic centres reveal an S absolute configuration. The two oxazolidinone rings are in an envelope conformation with...

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Detalles Bibliográficos
Autores principales: Berredjem, Malika, Allaoui, Assia, Direm, Amani, Aouf, Noureddine, Benali-Cherif, Nourredine
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007004/
https://www.ncbi.nlm.nih.gov/pubmed/21587844
http://dx.doi.org/10.1107/S1600536810020866
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author Berredjem, Malika
Allaoui, Assia
Direm, Amani
Aouf, Noureddine
Benali-Cherif, Nourredine
author_facet Berredjem, Malika
Allaoui, Assia
Direm, Amani
Aouf, Noureddine
Benali-Cherif, Nourredine
author_sort Berredjem, Malika
collection PubMed
description The title compound, C(21)H(21)N(3)O(7)S, contains an oxazolidinone ring and a sulfonamide group, both characteristic for biologically and pharrmaceutically active compounds. Both stereogenic centres reveal an S absolute configuration. The two oxazolidinone rings are in an envelope conformation with the methyl­ene carbon flap atoms deviating by 0.428 (1) and 0.364 (2) Å from the best least-square planes formed by the four other ring atoms. An intra­molecular N—H⋯O hydrogen bond contributes to the folded conformation of the mol­ecule. In the crystal, weak inter­molecular C—H⋯O inter­actions connect the mol­ecules into helices along the the twofold screw axes.
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spelling pubmed-30070042010-12-30 (4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfon­yl}-2-oxo-1,3-oxazolidine-3-carboxamide Berredjem, Malika Allaoui, Assia Direm, Amani Aouf, Noureddine Benali-Cherif, Nourredine Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(21)H(21)N(3)O(7)S, contains an oxazolidinone ring and a sulfonamide group, both characteristic for biologically and pharrmaceutically active compounds. Both stereogenic centres reveal an S absolute configuration. The two oxazolidinone rings are in an envelope conformation with the methyl­ene carbon flap atoms deviating by 0.428 (1) and 0.364 (2) Å from the best least-square planes formed by the four other ring atoms. An intra­molecular N—H⋯O hydrogen bond contributes to the folded conformation of the mol­ecule. In the crystal, weak inter­molecular C—H⋯O inter­actions connect the mol­ecules into helices along the the twofold screw axes. International Union of Crystallography 2010-06-09 /pmc/articles/PMC3007004/ /pubmed/21587844 http://dx.doi.org/10.1107/S1600536810020866 Text en © Berredjem et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Berredjem, Malika
Allaoui, Assia
Direm, Amani
Aouf, Noureddine
Benali-Cherif, Nourredine
(4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfon­yl}-2-oxo-1,3-oxazolidine-3-carboxamide
title (4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfon­yl}-2-oxo-1,3-oxazolidine-3-carboxamide
title_full (4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfon­yl}-2-oxo-1,3-oxazolidine-3-carboxamide
title_fullStr (4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfon­yl}-2-oxo-1,3-oxazolidine-3-carboxamide
title_full_unstemmed (4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfon­yl}-2-oxo-1,3-oxazolidine-3-carboxamide
title_short (4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfon­yl}-2-oxo-1,3-oxazolidine-3-carboxamide
title_sort (4s)-4-benzyl-n-{[(4s)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]sulfon­yl}-2-oxo-1,3-oxazolidine-3-carboxamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007004/
https://www.ncbi.nlm.nih.gov/pubmed/21587844
http://dx.doi.org/10.1107/S1600536810020866
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