Methyl 2-[(4-chloro-2-meth­oxy-5-oxo-2,5-dihydro­furan-3-yl)amino]­acetate

The title compound, C(8)H(10)ClNO(5), was obtained via a tandem Michael addition–elimination reaction of 3,4-dichloro-5-meth­oxy­furan-2(5H)-one and glycine methyl ester in the presence of triethyl­amine. The mol­ecular structure contains an approximately planar [maximum atomic deviation = 0.010 (2)...

Descripción completa

Detalles Bibliográficos
Autores principales: Mo, Yang-Qing, Wang, Zhao-Yang, Fu, Jian-Hua, Fang, Hua-Cai
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007059/
https://www.ncbi.nlm.nih.gov/pubmed/21588054
http://dx.doi.org/10.1107/S160053681002461X
_version_ 1782194287918710784
author Mo, Yang-Qing
Wang, Zhao-Yang
Fu, Jian-Hua
Fang, Hua-Cai
author_facet Mo, Yang-Qing
Wang, Zhao-Yang
Fu, Jian-Hua
Fang, Hua-Cai
author_sort Mo, Yang-Qing
collection PubMed
description The title compound, C(8)H(10)ClNO(5), was obtained via a tandem Michael addition–elimination reaction of 3,4-dichloro-5-meth­oxy­furan-2(5H)-one and glycine methyl ester in the presence of triethyl­amine. The mol­ecular structure contains an approximately planar [maximum atomic deviation = 0.010 (2) Å] five-membered furan­one ring. The crystal packing is stabilized by inter­molecular N—H⋯O and weak C—H⋯O hydrogen bonding.
format Text
id pubmed-3007059
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-30070592010-12-30 Methyl 2-[(4-chloro-2-meth­oxy-5-oxo-2,5-dihydro­furan-3-yl)amino]­acetate Mo, Yang-Qing Wang, Zhao-Yang Fu, Jian-Hua Fang, Hua-Cai Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(8)H(10)ClNO(5), was obtained via a tandem Michael addition–elimination reaction of 3,4-dichloro-5-meth­oxy­furan-2(5H)-one and glycine methyl ester in the presence of triethyl­amine. The mol­ecular structure contains an approximately planar [maximum atomic deviation = 0.010 (2) Å] five-membered furan­one ring. The crystal packing is stabilized by inter­molecular N—H⋯O and weak C—H⋯O hydrogen bonding. International Union of Crystallography 2010-06-30 /pmc/articles/PMC3007059/ /pubmed/21588054 http://dx.doi.org/10.1107/S160053681002461X Text en © Mo et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Mo, Yang-Qing
Wang, Zhao-Yang
Fu, Jian-Hua
Fang, Hua-Cai
Methyl 2-[(4-chloro-2-meth­oxy-5-oxo-2,5-dihydro­furan-3-yl)amino]­acetate
title Methyl 2-[(4-chloro-2-meth­oxy-5-oxo-2,5-dihydro­furan-3-yl)amino]­acetate
title_full Methyl 2-[(4-chloro-2-meth­oxy-5-oxo-2,5-dihydro­furan-3-yl)amino]­acetate
title_fullStr Methyl 2-[(4-chloro-2-meth­oxy-5-oxo-2,5-dihydro­furan-3-yl)amino]­acetate
title_full_unstemmed Methyl 2-[(4-chloro-2-meth­oxy-5-oxo-2,5-dihydro­furan-3-yl)amino]­acetate
title_short Methyl 2-[(4-chloro-2-meth­oxy-5-oxo-2,5-dihydro­furan-3-yl)amino]­acetate
title_sort methyl 2-[(4-chloro-2-meth­oxy-5-oxo-2,5-dihydro­furan-3-yl)amino]­acetate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007059/
https://www.ncbi.nlm.nih.gov/pubmed/21588054
http://dx.doi.org/10.1107/S160053681002461X
work_keys_str_mv AT moyangqing methyl24chloro2methoxy5oxo25dihydrofuran3ylaminoacetate
AT wangzhaoyang methyl24chloro2methoxy5oxo25dihydrofuran3ylaminoacetate
AT fujianhua methyl24chloro2methoxy5oxo25dihydrofuran3ylaminoacetate
AT fanghuacai methyl24chloro2methoxy5oxo25dihydrofuran3ylaminoacetate

Ejemplares similares