Reactivation of epigenetically silenced HER4/ERBB4 results in apoptosis of breast tumor cells

Experimental and clinical data support a growth inhibitory role for HER4 in breast cancer. Clinically HER4 expression is extinguished during breast tumorigenesis supporting a tumor suppressor function for HER4, however, a molecular mechanism to explain the selective loss of HER4 expression has remai...

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Detalles Bibliográficos
Autores principales: Das, P M, Thor, A D, Edgerton, S M, Barry, S K, Chen, D F, Jones, F E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007096/
https://www.ncbi.nlm.nih.gov/pubmed/20603612
http://dx.doi.org/10.1038/onc.2010.271

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