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3β,11α-Dihy­droxy-17a-oxa-d-homoandrost-5-en-17-one

The title compound, C(19)H(28)O(4), was prepared from DHEA (dehydro­epiandrosterone) by its biotransformation using whole cells of the filamentous fungus Beauveria bassiana. The asymmetric unit contains two mol­ecules. The lactone ring is trans-positioned to the neighboring six-membered ring. In the...

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Detalles Bibliográficos
Autores principales: Świzdor, Alina, Białońska, Agata, Kołek, Teresa, Panek, Anna
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007275/
https://www.ncbi.nlm.nih.gov/pubmed/21588317
http://dx.doi.org/10.1107/S1600536810026516
Descripción
Sumario:The title compound, C(19)H(28)O(4), was prepared from DHEA (dehydro­epiandrosterone) by its biotransformation using whole cells of the filamentous fungus Beauveria bassiana. The asymmetric unit contains two mol­ecules. The lactone ring is trans-positioned to the neighboring six-membered ring. In the crystal structure, O—H⋯O hydrogen bonds form layers, which are linked to each other by O—H⋯O and C—H⋯O hydrogen bonds.