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Ethyl 4-hy­droxy-2,6-diphenyl-1-(2-thio­morpholino­acet­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate

In the title compound, C(26)H(30)N(2)O(4)S, the thio­morpholine ring adopts a chair conformation whereas the tetra­hydro­pyridine ring is in a half-chair conformation. The dihedral angle between the two phenyl rings is 33.3 (2)°. A strong intra­molecular O—H⋯O hydrogen bond generates an S(6) motif....

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Detalles Bibliográficos
Autores principales: Aridoss, G., Sundaramoorthy, S., Velmurugan, D., Park, K. S., Jeong, Y. T.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007352/
https://www.ncbi.nlm.nih.gov/pubmed/21588298
http://dx.doi.org/10.1107/S1600536810026413
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author Aridoss, G.
Sundaramoorthy, S.
Velmurugan, D.
Park, K. S.
Jeong, Y. T.
author_facet Aridoss, G.
Sundaramoorthy, S.
Velmurugan, D.
Park, K. S.
Jeong, Y. T.
author_sort Aridoss, G.
collection PubMed
description In the title compound, C(26)H(30)N(2)O(4)S, the thio­morpholine ring adopts a chair conformation whereas the tetra­hydro­pyridine ring is in a half-chair conformation. The dihedral angle between the two phenyl rings is 33.3 (2)°. A strong intra­molecular O—H⋯O hydrogen bond generates an S(6) motif. In the crystal, mol­ecules are linked by inter­molecular C—H⋯O hydrogen bonds, generating a ribbon-like structure propagating along the a axis.
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spelling pubmed-30073522010-12-30 Ethyl 4-hy­droxy-2,6-diphenyl-1-(2-thio­morpholino­acet­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate Aridoss, G. Sundaramoorthy, S. Velmurugan, D. Park, K. S. Jeong, Y. T. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(26)H(30)N(2)O(4)S, the thio­morpholine ring adopts a chair conformation whereas the tetra­hydro­pyridine ring is in a half-chair conformation. The dihedral angle between the two phenyl rings is 33.3 (2)°. A strong intra­molecular O—H⋯O hydrogen bond generates an S(6) motif. In the crystal, mol­ecules are linked by inter­molecular C—H⋯O hydrogen bonds, generating a ribbon-like structure propagating along the a axis. International Union of Crystallography 2010-07-10 /pmc/articles/PMC3007352/ /pubmed/21588298 http://dx.doi.org/10.1107/S1600536810026413 Text en © Aridoss et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Aridoss, G.
Sundaramoorthy, S.
Velmurugan, D.
Park, K. S.
Jeong, Y. T.
Ethyl 4-hy­droxy-2,6-diphenyl-1-(2-thio­morpholino­acet­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title Ethyl 4-hy­droxy-2,6-diphenyl-1-(2-thio­morpholino­acet­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_full Ethyl 4-hy­droxy-2,6-diphenyl-1-(2-thio­morpholino­acet­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_fullStr Ethyl 4-hy­droxy-2,6-diphenyl-1-(2-thio­morpholino­acet­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_full_unstemmed Ethyl 4-hy­droxy-2,6-diphenyl-1-(2-thio­morpholino­acet­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_short Ethyl 4-hy­droxy-2,6-diphenyl-1-(2-thio­morpholino­acet­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_sort ethyl 4-hy­droxy-2,6-diphenyl-1-(2-thio­morpholino­acet­yl)-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007352/
https://www.ncbi.nlm.nih.gov/pubmed/21588298
http://dx.doi.org/10.1107/S1600536810026413
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AT velmurugand ethyl4hydroxy26diphenyl12thiomorpholinoacetyl1256tetrahydropyridine3carboxylate
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AT jeongyt ethyl4hydroxy26diphenyl12thiomorpholinoacetyl1256tetrahydropyridine3carboxylate