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(E)-1-(4-Amino­phen­yl)-3-(2,4,5-trimeth­oxy­phen­yl)prop-2-en-1-one

Mol­ecules of the title amino­chalcone, C(18)H(19)NO(4), are twisted, with a dihedral angle of 11.26 (6)° between the 4-amino­phenyl and 2,4,5-trimeth­oxy­phenyl rings. The conformations of the three meth­oxy groups with respect to the benzene ring are slightly different. Two meth­oxy groups are alm...

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Detalles Bibliográficos
Autores principales: Fun, Hoong-Kun, Kobkeatthawin, Thawanrat, Ruanwas, Pumsak, Chantrapromma, Suchada
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007376/
https://www.ncbi.nlm.nih.gov/pubmed/21588292
http://dx.doi.org/10.1107/S1600536810026346
Descripción
Sumario:Mol­ecules of the title amino­chalcone, C(18)H(19)NO(4), are twisted, with a dihedral angle of 11.26 (6)° between the 4-amino­phenyl and 2,4,5-trimeth­oxy­phenyl rings. The conformations of the three meth­oxy groups with respect to the benzene ring are slightly different. Two meth­oxy groups are almost coplanar with the attached benzene ring [C—O—C—C torsion angles of −1.45 (19) and 1.5 (2)°], while the third is (−)-synclinal with the attached benzene ring [C—O—C—C = −81.36 (17)°]. In the crystal structure, mol­ecules are stacked into columns along the b axis and mol­ecules in adjacent columns are linked by N—H⋯O hydrogen bonds into V-shaped double columns. Weak π–π inter­actions are also observed, with a centroid-centroid distance of 3.7532 (8) Å.