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Ep­oxy­cytochalasin H methanol solvate

In the title solvate, C(30)H(39)NO(5)·CH(4)O {systematic name: 21-acet­oxy-18,21-dihy­droxy-5,6,16,18-tetra­methyl-10-phenyl-6,7-ep­oxy-[11]cytochalasa-13,19-dien-1-one methanol solvate}, the organic mol­ecule exhibits the tetra­cyclic terpenoid skeleton of cytochalasin, consisting of fused five-, s...

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Detalles Bibliográficos
Autores principales: Li, Li-mei, Liu, Yang, Yang, Tai, Yu, Kai-bei, Zou, Qiang
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007521/
https://www.ncbi.nlm.nih.gov/pubmed/21588456
http://dx.doi.org/10.1107/S1600536810029600
Descripción
Sumario:In the title solvate, C(30)H(39)NO(5)·CH(4)O {systematic name: 21-acet­oxy-18,21-dihy­droxy-5,6,16,18-tetra­methyl-10-phenyl-6,7-ep­oxy-[11]cytochalasa-13,19-dien-1-one methanol solvate}, the organic mol­ecule exhibits the tetra­cyclic terpenoid skeleton of cytochalasin, consisting of fused five-, six-, three- and 11-membered rings. The five-membered ring adopts an envelope conformation, while the six-membered ring is in a boat conformation. The ep­oxy O atom on the six-membered ring is pointing away from the five-membered ring. An inter­stitial methanol solvent mol­ecule is hydrogen bonded to the cytochalasin mol­ecules and inter­molecular O—H⋯O and N—H⋯O hydrogen bonds connect the mol­ecules into infinite chains along the ([Image: see text]10) direction.