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Ep­oxy­cytochalasin H methanol solvate

In the title solvate, C(30)H(39)NO(5)·CH(4)O {systematic name: 21-acet­oxy-18,21-dihy­droxy-5,6,16,18-tetra­methyl-10-phenyl-6,7-ep­oxy-[11]cytochalasa-13,19-dien-1-one methanol solvate}, the organic mol­ecule exhibits the tetra­cyclic terpenoid skeleton of cytochalasin, consisting of fused five-, s...

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Detalles Bibliográficos
Autores principales: Li, Li-mei, Liu, Yang, Yang, Tai, Yu, Kai-bei, Zou, Qiang
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007521/
https://www.ncbi.nlm.nih.gov/pubmed/21588456
http://dx.doi.org/10.1107/S1600536810029600
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author Li, Li-mei
Liu, Yang
Yang, Tai
Yu, Kai-bei
Zou, Qiang
author_facet Li, Li-mei
Liu, Yang
Yang, Tai
Yu, Kai-bei
Zou, Qiang
author_sort Li, Li-mei
collection PubMed
description In the title solvate, C(30)H(39)NO(5)·CH(4)O {systematic name: 21-acet­oxy-18,21-dihy­droxy-5,6,16,18-tetra­methyl-10-phenyl-6,7-ep­oxy-[11]cytochalasa-13,19-dien-1-one methanol solvate}, the organic mol­ecule exhibits the tetra­cyclic terpenoid skeleton of cytochalasin, consisting of fused five-, six-, three- and 11-membered rings. The five-membered ring adopts an envelope conformation, while the six-membered ring is in a boat conformation. The ep­oxy O atom on the six-membered ring is pointing away from the five-membered ring. An inter­stitial methanol solvent mol­ecule is hydrogen bonded to the cytochalasin mol­ecules and inter­molecular O—H⋯O and N—H⋯O hydrogen bonds connect the mol­ecules into infinite chains along the ([Image: see text]10) direction.
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spelling pubmed-30075212010-12-30 Ep­oxy­cytochalasin H methanol solvate Li, Li-mei Liu, Yang Yang, Tai Yu, Kai-bei Zou, Qiang Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title solvate, C(30)H(39)NO(5)·CH(4)O {systematic name: 21-acet­oxy-18,21-dihy­droxy-5,6,16,18-tetra­methyl-10-phenyl-6,7-ep­oxy-[11]cytochalasa-13,19-dien-1-one methanol solvate}, the organic mol­ecule exhibits the tetra­cyclic terpenoid skeleton of cytochalasin, consisting of fused five-, six-, three- and 11-membered rings. The five-membered ring adopts an envelope conformation, while the six-membered ring is in a boat conformation. The ep­oxy O atom on the six-membered ring is pointing away from the five-membered ring. An inter­stitial methanol solvent mol­ecule is hydrogen bonded to the cytochalasin mol­ecules and inter­molecular O—H⋯O and N—H⋯O hydrogen bonds connect the mol­ecules into infinite chains along the ([Image: see text]10) direction. International Union of Crystallography 2010-07-31 /pmc/articles/PMC3007521/ /pubmed/21588456 http://dx.doi.org/10.1107/S1600536810029600 Text en © Li et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Li, Li-mei
Liu, Yang
Yang, Tai
Yu, Kai-bei
Zou, Qiang
Ep­oxy­cytochalasin H methanol solvate
title Ep­oxy­cytochalasin H methanol solvate
title_full Ep­oxy­cytochalasin H methanol solvate
title_fullStr Ep­oxy­cytochalasin H methanol solvate
title_full_unstemmed Ep­oxy­cytochalasin H methanol solvate
title_short Ep­oxy­cytochalasin H methanol solvate
title_sort ep­oxy­cytochalasin h methanol solvate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007521/
https://www.ncbi.nlm.nih.gov/pubmed/21588456
http://dx.doi.org/10.1107/S1600536810029600
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AT liuyang epoxycytochalasinhmethanolsolvate
AT yangtai epoxycytochalasinhmethanolsolvate
AT yukaibei epoxycytochalasinhmethanolsolvate
AT zouqiang epoxycytochalasinhmethanolsolvate