Cargando…
Epoxycytochalasin H methanol solvate
In the title solvate, C(30)H(39)NO(5)·CH(4)O {systematic name: 21-acetoxy-18,21-dihydroxy-5,6,16,18-tetramethyl-10-phenyl-6,7-epoxy-[11]cytochalasa-13,19-dien-1-one methanol solvate}, the organic molecule exhibits the tetracyclic terpenoid skeleton of cytochalasin, consisting of fused five-, s...
Autores principales: | , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007521/ https://www.ncbi.nlm.nih.gov/pubmed/21588456 http://dx.doi.org/10.1107/S1600536810029600 |
_version_ | 1782194377754411008 |
---|---|
author | Li, Li-mei Liu, Yang Yang, Tai Yu, Kai-bei Zou, Qiang |
author_facet | Li, Li-mei Liu, Yang Yang, Tai Yu, Kai-bei Zou, Qiang |
author_sort | Li, Li-mei |
collection | PubMed |
description | In the title solvate, C(30)H(39)NO(5)·CH(4)O {systematic name: 21-acetoxy-18,21-dihydroxy-5,6,16,18-tetramethyl-10-phenyl-6,7-epoxy-[11]cytochalasa-13,19-dien-1-one methanol solvate}, the organic molecule exhibits the tetracyclic terpenoid skeleton of cytochalasin, consisting of fused five-, six-, three- and 11-membered rings. The five-membered ring adopts an envelope conformation, while the six-membered ring is in a boat conformation. The epoxy O atom on the six-membered ring is pointing away from the five-membered ring. An interstitial methanol solvent molecule is hydrogen bonded to the cytochalasin molecules and intermolecular O—H⋯O and N—H⋯O hydrogen bonds connect the molecules into infinite chains along the ([Image: see text]10) direction. |
format | Text |
id | pubmed-3007521 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-30075212010-12-30 Epoxycytochalasin H methanol solvate Li, Li-mei Liu, Yang Yang, Tai Yu, Kai-bei Zou, Qiang Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title solvate, C(30)H(39)NO(5)·CH(4)O {systematic name: 21-acetoxy-18,21-dihydroxy-5,6,16,18-tetramethyl-10-phenyl-6,7-epoxy-[11]cytochalasa-13,19-dien-1-one methanol solvate}, the organic molecule exhibits the tetracyclic terpenoid skeleton of cytochalasin, consisting of fused five-, six-, three- and 11-membered rings. The five-membered ring adopts an envelope conformation, while the six-membered ring is in a boat conformation. The epoxy O atom on the six-membered ring is pointing away from the five-membered ring. An interstitial methanol solvent molecule is hydrogen bonded to the cytochalasin molecules and intermolecular O—H⋯O and N—H⋯O hydrogen bonds connect the molecules into infinite chains along the ([Image: see text]10) direction. International Union of Crystallography 2010-07-31 /pmc/articles/PMC3007521/ /pubmed/21588456 http://dx.doi.org/10.1107/S1600536810029600 Text en © Li et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Li, Li-mei Liu, Yang Yang, Tai Yu, Kai-bei Zou, Qiang Epoxycytochalasin H methanol solvate |
title | Epoxycytochalasin H methanol solvate |
title_full | Epoxycytochalasin H methanol solvate |
title_fullStr | Epoxycytochalasin H methanol solvate |
title_full_unstemmed | Epoxycytochalasin H methanol solvate |
title_short | Epoxycytochalasin H methanol solvate |
title_sort | epoxycytochalasin h methanol solvate |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007521/ https://www.ncbi.nlm.nih.gov/pubmed/21588456 http://dx.doi.org/10.1107/S1600536810029600 |
work_keys_str_mv | AT lilimei epoxycytochalasinhmethanolsolvate AT liuyang epoxycytochalasinhmethanolsolvate AT yangtai epoxycytochalasinhmethanolsolvate AT yukaibei epoxycytochalasinhmethanolsolvate AT zouqiang epoxycytochalasinhmethanolsolvate |