1-[4-(3,5-Difluoro­benz­yloxy)-2-hy­droxy­phen­yl]ethanone

The title compound, C(15)H(12)F(2)O(3), has been obtained by the reaction of 2,4-dihy­droxy­lacetonephenone, potassium carbonate and 3,5-difluoro­benzyl bromide. The hy­droxy group is involved in an intra­molecular O—H⋯O hydrogen bond in each of the two independent mol­ecules in the asymmetric unit....

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Detalles Bibliográficos
Autores principales: Ma, Ya-Tuan, Zhang, An-Ling, Yuan, Mao-Sen, Gao, Jin-Ming
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007899/
https://www.ncbi.nlm.nih.gov/pubmed/21588786
http://dx.doi.org/10.1107/S1600536810033787
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author Ma, Ya-Tuan
Zhang, An-Ling
Yuan, Mao-Sen
Gao, Jin-Ming
author_facet Ma, Ya-Tuan
Zhang, An-Ling
Yuan, Mao-Sen
Gao, Jin-Ming
author_sort Ma, Ya-Tuan
collection PubMed
description The title compound, C(15)H(12)F(2)O(3), has been obtained by the reaction of 2,4-dihy­droxy­lacetonephenone, potassium carbonate and 3,5-difluoro­benzyl bromide. The hy­droxy group is involved in an intra­molecular O—H⋯O hydrogen bond in each of the two independent mol­ecules in the asymmetric unit. The dihedral angle between the aromatic rings is 0.5 (2)° in one molecule and 1.9 (2)° in the other. In the crystal, weak C—H⋯O inter­actions link the mol­ecules into tetra­meric units aligned perpendicular to b.
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spelling pubmed-30078992010-12-30 1-[4-(3,5-Difluoro­benz­yloxy)-2-hy­droxy­phen­yl]ethanone Ma, Ya-Tuan Zhang, An-Ling Yuan, Mao-Sen Gao, Jin-Ming Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(15)H(12)F(2)O(3), has been obtained by the reaction of 2,4-dihy­droxy­lacetonephenone, potassium carbonate and 3,5-difluoro­benzyl bromide. The hy­droxy group is involved in an intra­molecular O—H⋯O hydrogen bond in each of the two independent mol­ecules in the asymmetric unit. The dihedral angle between the aromatic rings is 0.5 (2)° in one molecule and 1.9 (2)° in the other. In the crystal, weak C—H⋯O inter­actions link the mol­ecules into tetra­meric units aligned perpendicular to b. International Union of Crystallography 2010-08-28 /pmc/articles/PMC3007899/ /pubmed/21588786 http://dx.doi.org/10.1107/S1600536810033787 Text en © Ma et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Ma, Ya-Tuan
Zhang, An-Ling
Yuan, Mao-Sen
Gao, Jin-Ming
1-[4-(3,5-Difluoro­benz­yloxy)-2-hy­droxy­phen­yl]ethanone
title 1-[4-(3,5-Difluoro­benz­yloxy)-2-hy­droxy­phen­yl]ethanone
title_full 1-[4-(3,5-Difluoro­benz­yloxy)-2-hy­droxy­phen­yl]ethanone
title_fullStr 1-[4-(3,5-Difluoro­benz­yloxy)-2-hy­droxy­phen­yl]ethanone
title_full_unstemmed 1-[4-(3,5-Difluoro­benz­yloxy)-2-hy­droxy­phen­yl]ethanone
title_short 1-[4-(3,5-Difluoro­benz­yloxy)-2-hy­droxy­phen­yl]ethanone
title_sort 1-[4-(3,5-difluoro­benz­yloxy)-2-hy­droxy­phen­yl]ethanone
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007899/
https://www.ncbi.nlm.nih.gov/pubmed/21588786
http://dx.doi.org/10.1107/S1600536810033787
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AT zhanganling 1435difluorobenzyloxy2hydroxyphenylethanone
AT yuanmaosen 1435difluorobenzyloxy2hydroxyphenylethanone
AT gaojinming 1435difluorobenzyloxy2hydroxyphenylethanone

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