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1′-Acetyl-3-phenyl-6-oxa-4-thia-2-azaspiro[bicyclo[3.2.0]hept-2-ene-7,3′-indolin]-2′-one
In the title indoline compound, C(19)H(14)N(2)O(3)S, the pyrrolidine ring adopts an envelope conformation with the four-connected (spiro) C atom as the flap [displacement = 0.148 (3) Å]. The mean plane formed through the indoline unit is inclined at dihedral angles of 89.92 (16) and 59.54 (12)° with...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007916/ https://www.ncbi.nlm.nih.gov/pubmed/21588619 http://dx.doi.org/10.1107/S1600536810031016 |
Sumario: | In the title indoline compound, C(19)H(14)N(2)O(3)S, the pyrrolidine ring adopts an envelope conformation with the four-connected (spiro) C atom as the flap [displacement = 0.148 (3) Å]. The mean plane formed through the indoline unit is inclined at dihedral angles of 89.92 (16) and 59.54 (12)° with the thiazole and phenyl rings, respectively; the dihedral angle between the latter rings is 9.55 (14)°. In the crystal, pairs of intermolecular C—H⋯O hydrogen bonds link neighbouring molecules into inversion dimers, producing R (2) (2)(6) hydrogen-bond ring motifs. Weak intermolecular C—H⋯π as well as π–π interactions [centroid–centroid distance = 3.4041 (15) Å] further consolidate the crystal structure. |
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