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1′-Acetyl-3-phenyl-6-oxa-4-thia-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,3′-indolin]-2′-one

In the title indoline compound, C(19)H(14)N(2)O(3)S, the pyrrolidine ring adopts an envelope conformation with the four-connected (spiro) C atom as the flap [displacement = 0.148 (3) Å]. The mean plane formed through the indoline unit is inclined at dihedral angles of 89.92 (16) and 59.54 (12)° with...

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Detalles Bibliográficos
Autores principales: Fun, Hoong-Kun, Goh, Jia Hao, Liu, Yang, Zhang, Yan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007916/
https://www.ncbi.nlm.nih.gov/pubmed/21588619
http://dx.doi.org/10.1107/S1600536810031016
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author Fun, Hoong-Kun
Goh, Jia Hao
Liu, Yang
Zhang, Yan
author_facet Fun, Hoong-Kun
Goh, Jia Hao
Liu, Yang
Zhang, Yan
author_sort Fun, Hoong-Kun
collection PubMed
description In the title indoline compound, C(19)H(14)N(2)O(3)S, the pyrrolidine ring adopts an envelope conformation with the four-connected (spiro) C atom as the flap [displacement = 0.148 (3) Å]. The mean plane formed through the indoline unit is inclined at dihedral angles of 89.92 (16) and 59.54 (12)° with the thia­zole and phenyl rings, respectively; the dihedral angle between the latter rings is 9.55 (14)°. In the crystal, pairs of inter­molecular C—H⋯O hydrogen bonds link neighbouring mol­ecules into inversion dimers, producing R (2) (2)(6) hydrogen-bond ring motifs. Weak inter­molecular C—H⋯π as well as π–π inter­actions [centroid–centroid distance = 3.4041 (15) Å] further consolidate the crystal structure.
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spelling pubmed-30079162010-12-30 1′-Acetyl-3-phenyl-6-oxa-4-thia-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,3′-indolin]-2′-one Fun, Hoong-Kun Goh, Jia Hao Liu, Yang Zhang, Yan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title indoline compound, C(19)H(14)N(2)O(3)S, the pyrrolidine ring adopts an envelope conformation with the four-connected (spiro) C atom as the flap [displacement = 0.148 (3) Å]. The mean plane formed through the indoline unit is inclined at dihedral angles of 89.92 (16) and 59.54 (12)° with the thia­zole and phenyl rings, respectively; the dihedral angle between the latter rings is 9.55 (14)°. In the crystal, pairs of inter­molecular C—H⋯O hydrogen bonds link neighbouring mol­ecules into inversion dimers, producing R (2) (2)(6) hydrogen-bond ring motifs. Weak inter­molecular C—H⋯π as well as π–π inter­actions [centroid–centroid distance = 3.4041 (15) Å] further consolidate the crystal structure. International Union of Crystallography 2010-08-11 /pmc/articles/PMC3007916/ /pubmed/21588619 http://dx.doi.org/10.1107/S1600536810031016 Text en © Fun et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Fun, Hoong-Kun
Goh, Jia Hao
Liu, Yang
Zhang, Yan
1′-Acetyl-3-phenyl-6-oxa-4-thia-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,3′-indolin]-2′-one
title 1′-Acetyl-3-phenyl-6-oxa-4-thia-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,3′-indolin]-2′-one
title_full 1′-Acetyl-3-phenyl-6-oxa-4-thia-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,3′-indolin]-2′-one
title_fullStr 1′-Acetyl-3-phenyl-6-oxa-4-thia-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,3′-indolin]-2′-one
title_full_unstemmed 1′-Acetyl-3-phenyl-6-oxa-4-thia-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,3′-indolin]-2′-one
title_short 1′-Acetyl-3-phenyl-6-oxa-4-thia-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,3′-indolin]-2′-one
title_sort 1′-acetyl-3-phenyl-6-oxa-4-thia-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,3′-indolin]-2′-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007916/
https://www.ncbi.nlm.nih.gov/pubmed/21588619
http://dx.doi.org/10.1107/S1600536810031016
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