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3-Phenyl-2-(pyrrolidin-1-yl)-5,6-dihydro-8H-thio­pyrano[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3H)-one

In the title compound, C(19)H(19)N(3)OS(2), the thio­pyran ring adopts a twist-chair conformation and the pyrimidinone unit is essentially planar, with a mean deviation of 0.0497 Å. The thio­phene ring is essentially planar with a maximum deviation of 0.024 (2) Å, while the pyrrolidine ring exhibits...

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Detalles Bibliográficos
Autores principales: Meng, Shuang-Ming, Xie, Hai, Fan, Yue-Qin, Jing, Bu-qin, Guo, Yong
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007963/
https://www.ncbi.nlm.nih.gov/pubmed/21588734
http://dx.doi.org/10.1107/S1600536810032794
Descripción
Sumario:In the title compound, C(19)H(19)N(3)OS(2), the thio­pyran ring adopts a twist-chair conformation and the pyrimidinone unit is essentially planar, with a mean deviation of 0.0497 Å. The thio­phene ring is essentially planar with a maximum deviation of 0.024 (2) Å, while the pyrrolidine ring exhibits an envelope conformation. The pyrimidinone and thio­phene rings are almost coplanar, forming a dihedral angle of 6.31 (15)°, while the dihedral angle between the mean planes of the phenyl ring and the pyrimidinone ring is 68.13 (10)°. In the crystal structure, adjacent mol­ecules are linked by C—H⋯O hydrogen bonds, forming a two-dimensional network in the ac plane.