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Methyl 2-(tert-butoxycarbonylamino)-1,3-thiazole-5-carboxylate
The title compound, C(10)H(14)N(2)O(4)S, was synthesized by the reaction of methyl 2-aminothiazole-5-carboxylate and di-tert-butyl carbonate. In this structure, the thiazole ring is planar (mean deviation = 0.0011 Å). Two weak intramolecular C—H⋯O hydrogen bonds are formed between two of the me...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007983/ https://www.ncbi.nlm.nih.gov/pubmed/21588688 http://dx.doi.org/10.1107/S1600536810032277 |
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author | An, Kang Guan, Jiannin Yu, Pen Yang, Hao Wan, Rong |
author_facet | An, Kang Guan, Jiannin Yu, Pen Yang, Hao Wan, Rong |
author_sort | An, Kang |
collection | PubMed |
description | The title compound, C(10)H(14)N(2)O(4)S, was synthesized by the reaction of methyl 2-aminothiazole-5-carboxylate and di-tert-butyl carbonate. In this structure, the thiazole ring is planar (mean deviation = 0.0011 Å). Two weak intramolecular C—H⋯O hydrogen bonds are formed between two of the methyl groups and one carbonyl O atom, resulting in the formation of two twisted six-membered rings. Intermolecular N—H⋯N hydrogen bonds link the molecules to form centrosymmetric dimeric units, and the hydrogen-bond scheme is completed by intermolecular C—H⋯O contacts. |
format | Text |
id | pubmed-3007983 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-30079832010-12-30 Methyl 2-(tert-butoxycarbonylamino)-1,3-thiazole-5-carboxylate An, Kang Guan, Jiannin Yu, Pen Yang, Hao Wan, Rong Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(10)H(14)N(2)O(4)S, was synthesized by the reaction of methyl 2-aminothiazole-5-carboxylate and di-tert-butyl carbonate. In this structure, the thiazole ring is planar (mean deviation = 0.0011 Å). Two weak intramolecular C—H⋯O hydrogen bonds are formed between two of the methyl groups and one carbonyl O atom, resulting in the formation of two twisted six-membered rings. Intermolecular N—H⋯N hydrogen bonds link the molecules to form centrosymmetric dimeric units, and the hydrogen-bond scheme is completed by intermolecular C—H⋯O contacts. International Union of Crystallography 2010-08-18 /pmc/articles/PMC3007983/ /pubmed/21588688 http://dx.doi.org/10.1107/S1600536810032277 Text en © An et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers An, Kang Guan, Jiannin Yu, Pen Yang, Hao Wan, Rong Methyl 2-(tert-butoxycarbonylamino)-1,3-thiazole-5-carboxylate |
title | Methyl 2-(tert-butoxycarbonylamino)-1,3-thiazole-5-carboxylate |
title_full | Methyl 2-(tert-butoxycarbonylamino)-1,3-thiazole-5-carboxylate |
title_fullStr | Methyl 2-(tert-butoxycarbonylamino)-1,3-thiazole-5-carboxylate |
title_full_unstemmed | Methyl 2-(tert-butoxycarbonylamino)-1,3-thiazole-5-carboxylate |
title_short | Methyl 2-(tert-butoxycarbonylamino)-1,3-thiazole-5-carboxylate |
title_sort | methyl 2-(tert-butoxycarbonylamino)-1,3-thiazole-5-carboxylate |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3007983/ https://www.ncbi.nlm.nih.gov/pubmed/21588688 http://dx.doi.org/10.1107/S1600536810032277 |
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