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{4-[(7-Chloro-4-quinol­yl)amino]-N,N-di­ethyl­penta­naminium}(triphenyl­phos­phine)gold(I) dinitrate

The title compound, [Au(C(18)H(27)ClN(3))(C(18)H(15)P)](NO(3))(2), is a coordination complex of gold(I) triphenyl­phosphine with the N atom in the quinoline ring of the common anti­malarial compound chloro­quine (CQ). The pendant diethyl­amino group of the CQ ligand was found to be protonated. The c...

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Autores principales: Hitosugi-Levesque, Marina, Tanski, Joseph M.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008023/
https://www.ncbi.nlm.nih.gov/pubmed/21588511
http://dx.doi.org/10.1107/S1600536810031144
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author Hitosugi-Levesque, Marina
Tanski, Joseph M.
author_facet Hitosugi-Levesque, Marina
Tanski, Joseph M.
author_sort Hitosugi-Levesque, Marina
collection PubMed
description The title compound, [Au(C(18)H(27)ClN(3))(C(18)H(15)P)](NO(3))(2), is a coordination complex of gold(I) triphenyl­phosphine with the N atom in the quinoline ring of the common anti­malarial compound chloro­quine (CQ). The pendant diethyl­amino group of the CQ ligand was found to be protonated. The complex exhibits a nearly linear coordination geometry around the Au(I) atom [N—Au—P = 176.94 (6)°], with Au—N and Au—P bond lengths of 2.070 (2) and 2.2338 (7) Å, respectively. The diethylammonium group and one of the two nitrate counter-ions are disordered with occupancy ratios of 0.519 (4):0.481 (4). The nitrate anions are hydrogen bound to both the amino and ammonium groups of the N,N-diethylpentanaminium fragment of the CQ.
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spelling pubmed-30080232010-12-30 {4-[(7-Chloro-4-quinol­yl)amino]-N,N-di­ethyl­penta­naminium}(triphenyl­phos­phine)gold(I) dinitrate Hitosugi-Levesque, Marina Tanski, Joseph M. Acta Crystallogr Sect E Struct Rep Online Metal-Organic Papers The title compound, [Au(C(18)H(27)ClN(3))(C(18)H(15)P)](NO(3))(2), is a coordination complex of gold(I) triphenyl­phosphine with the N atom in the quinoline ring of the common anti­malarial compound chloro­quine (CQ). The pendant diethyl­amino group of the CQ ligand was found to be protonated. The complex exhibits a nearly linear coordination geometry around the Au(I) atom [N—Au—P = 176.94 (6)°], with Au—N and Au—P bond lengths of 2.070 (2) and 2.2338 (7) Å, respectively. The diethylammonium group and one of the two nitrate counter-ions are disordered with occupancy ratios of 0.519 (4):0.481 (4). The nitrate anions are hydrogen bound to both the amino and ammonium groups of the N,N-diethylpentanaminium fragment of the CQ. International Union of Crystallography 2010-08-18 /pmc/articles/PMC3008023/ /pubmed/21588511 http://dx.doi.org/10.1107/S1600536810031144 Text en © Hitosugi-Levesque and Tanski 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Metal-Organic Papers
Hitosugi-Levesque, Marina
Tanski, Joseph M.
{4-[(7-Chloro-4-quinol­yl)amino]-N,N-di­ethyl­penta­naminium}(triphenyl­phos­phine)gold(I) dinitrate
title {4-[(7-Chloro-4-quinol­yl)amino]-N,N-di­ethyl­penta­naminium}(triphenyl­phos­phine)gold(I) dinitrate
title_full {4-[(7-Chloro-4-quinol­yl)amino]-N,N-di­ethyl­penta­naminium}(triphenyl­phos­phine)gold(I) dinitrate
title_fullStr {4-[(7-Chloro-4-quinol­yl)amino]-N,N-di­ethyl­penta­naminium}(triphenyl­phos­phine)gold(I) dinitrate
title_full_unstemmed {4-[(7-Chloro-4-quinol­yl)amino]-N,N-di­ethyl­penta­naminium}(triphenyl­phos­phine)gold(I) dinitrate
title_short {4-[(7-Chloro-4-quinol­yl)amino]-N,N-di­ethyl­penta­naminium}(triphenyl­phos­phine)gold(I) dinitrate
title_sort {4-[(7-chloro-4-quinol­yl)amino]-n,n-di­ethyl­penta­naminium}(triphenyl­phos­phine)gold(i) dinitrate
topic Metal-Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008023/
https://www.ncbi.nlm.nih.gov/pubmed/21588511
http://dx.doi.org/10.1107/S1600536810031144
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