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{4-[(7-Chloro-4-quinolyl)amino]-N,N-diethylpentanaminium}(triphenylphosphine)gold(I) dinitrate
The title compound, [Au(C(18)H(27)ClN(3))(C(18)H(15)P)](NO(3))(2), is a coordination complex of gold(I) triphenylphosphine with the N atom in the quinoline ring of the common antimalarial compound chloroquine (CQ). The pendant diethylamino group of the CQ ligand was found to be protonated. The c...
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Formato: | Texto |
Lenguaje: | English |
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International Union of Crystallography
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008023/ https://www.ncbi.nlm.nih.gov/pubmed/21588511 http://dx.doi.org/10.1107/S1600536810031144 |
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author | Hitosugi-Levesque, Marina Tanski, Joseph M. |
author_facet | Hitosugi-Levesque, Marina Tanski, Joseph M. |
author_sort | Hitosugi-Levesque, Marina |
collection | PubMed |
description | The title compound, [Au(C(18)H(27)ClN(3))(C(18)H(15)P)](NO(3))(2), is a coordination complex of gold(I) triphenylphosphine with the N atom in the quinoline ring of the common antimalarial compound chloroquine (CQ). The pendant diethylamino group of the CQ ligand was found to be protonated. The complex exhibits a nearly linear coordination geometry around the Au(I) atom [N—Au—P = 176.94 (6)°], with Au—N and Au—P bond lengths of 2.070 (2) and 2.2338 (7) Å, respectively. The diethylammonium group and one of the two nitrate counter-ions are disordered with occupancy ratios of 0.519 (4):0.481 (4). The nitrate anions are hydrogen bound to both the amino and ammonium groups of the N,N-diethylpentanaminium fragment of the CQ. |
format | Text |
id | pubmed-3008023 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-30080232010-12-30 {4-[(7-Chloro-4-quinolyl)amino]-N,N-diethylpentanaminium}(triphenylphosphine)gold(I) dinitrate Hitosugi-Levesque, Marina Tanski, Joseph M. Acta Crystallogr Sect E Struct Rep Online Metal-Organic Papers The title compound, [Au(C(18)H(27)ClN(3))(C(18)H(15)P)](NO(3))(2), is a coordination complex of gold(I) triphenylphosphine with the N atom in the quinoline ring of the common antimalarial compound chloroquine (CQ). The pendant diethylamino group of the CQ ligand was found to be protonated. The complex exhibits a nearly linear coordination geometry around the Au(I) atom [N—Au—P = 176.94 (6)°], with Au—N and Au—P bond lengths of 2.070 (2) and 2.2338 (7) Å, respectively. The diethylammonium group and one of the two nitrate counter-ions are disordered with occupancy ratios of 0.519 (4):0.481 (4). The nitrate anions are hydrogen bound to both the amino and ammonium groups of the N,N-diethylpentanaminium fragment of the CQ. International Union of Crystallography 2010-08-18 /pmc/articles/PMC3008023/ /pubmed/21588511 http://dx.doi.org/10.1107/S1600536810031144 Text en © Hitosugi-Levesque and Tanski 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Metal-Organic Papers Hitosugi-Levesque, Marina Tanski, Joseph M. {4-[(7-Chloro-4-quinolyl)amino]-N,N-diethylpentanaminium}(triphenylphosphine)gold(I) dinitrate |
title | {4-[(7-Chloro-4-quinolyl)amino]-N,N-diethylpentanaminium}(triphenylphosphine)gold(I) dinitrate |
title_full | {4-[(7-Chloro-4-quinolyl)amino]-N,N-diethylpentanaminium}(triphenylphosphine)gold(I) dinitrate |
title_fullStr | {4-[(7-Chloro-4-quinolyl)amino]-N,N-diethylpentanaminium}(triphenylphosphine)gold(I) dinitrate |
title_full_unstemmed | {4-[(7-Chloro-4-quinolyl)amino]-N,N-diethylpentanaminium}(triphenylphosphine)gold(I) dinitrate |
title_short | {4-[(7-Chloro-4-quinolyl)amino]-N,N-diethylpentanaminium}(triphenylphosphine)gold(I) dinitrate |
title_sort | {4-[(7-chloro-4-quinolyl)amino]-n,n-diethylpentanaminium}(triphenylphosphine)gold(i) dinitrate |
topic | Metal-Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008023/ https://www.ncbi.nlm.nih.gov/pubmed/21588511 http://dx.doi.org/10.1107/S1600536810031144 |
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