Nifedipine–pyrazine (2/1)

In the title compound, 2C(17)H(18)N(2)O(6)·C(4)H(4)N(2) [systematic name: 3,5-dimethyl 2,6-dimethyl-4-(2-nitro­phen­yl)-1,4-di­hydro­pyridine-3,5-dicarboxyl­ate–pyrazine (2/1)], the complete pyrazine molecule is generated by crystallographic inversion symmetry. The center of the pyrazine ring lies o...

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Detalles Bibliográficos
Autores principales: Schultheiss, Nate, Roe, Melanie, Smit, Jared P.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008143/
https://www.ncbi.nlm.nih.gov/pubmed/21588649
http://dx.doi.org/10.1107/S1600536810031703
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author Schultheiss, Nate
Roe, Melanie
Smit, Jared P.
author_facet Schultheiss, Nate
Roe, Melanie
Smit, Jared P.
author_sort Schultheiss, Nate
collection PubMed
description In the title compound, 2C(17)H(18)N(2)O(6)·C(4)H(4)N(2) [systematic name: 3,5-dimethyl 2,6-dimethyl-4-(2-nitro­phen­yl)-1,4-di­hydro­pyridine-3,5-dicarboxyl­ate–pyrazine (2/1)], the complete pyrazine molecule is generated by crystallographic inversion symmetry. The center of the pyrazine ring lies on an inversion center. The nifedipine mol­ecules are linked into chains along the c axis through N—H⋯O hydrogen bonds, while the pyrazine mol­ecules are organized in the structure through van der Waals inter­actions.
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spelling pubmed-30081432010-12-30 Nifedipine–pyrazine (2/1) Schultheiss, Nate Roe, Melanie Smit, Jared P. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, 2C(17)H(18)N(2)O(6)·C(4)H(4)N(2) [systematic name: 3,5-dimethyl 2,6-dimethyl-4-(2-nitro­phen­yl)-1,4-di­hydro­pyridine-3,5-dicarboxyl­ate–pyrazine (2/1)], the complete pyrazine molecule is generated by crystallographic inversion symmetry. The center of the pyrazine ring lies on an inversion center. The nifedipine mol­ecules are linked into chains along the c axis through N—H⋯O hydrogen bonds, while the pyrazine mol­ecules are organized in the structure through van der Waals inter­actions. International Union of Crystallography 2010-08-11 /pmc/articles/PMC3008143/ /pubmed/21588649 http://dx.doi.org/10.1107/S1600536810031703 Text en © Schultheiss et al. 2010 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Schultheiss, Nate
Roe, Melanie
Smit, Jared P.
Nifedipine–pyrazine (2/1)
title Nifedipine–pyrazine (2/1)
title_full Nifedipine–pyrazine (2/1)
title_fullStr Nifedipine–pyrazine (2/1)
title_full_unstemmed Nifedipine–pyrazine (2/1)
title_short Nifedipine–pyrazine (2/1)
title_sort nifedipine–pyrazine (2/1)
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008143/
https://www.ncbi.nlm.nih.gov/pubmed/21588649
http://dx.doi.org/10.1107/S1600536810031703
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