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Topo2α protein expression predicts response to anthracycline combination neo-adjuvant chemotherapy in locally advanced primary breast cancer

BACKGROUND: This study aimed to identify predictors of response to anthracycline-based chemotherapy (5-fluoro-uracil, epirubicin, cyclophosphamide (FEC)) in locally advanced primary breast cancer (LAPC). METHODS: A total of 91 LAPC patients were treated with six cycles of FEC before surgery. Protein...

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Detalles Bibliográficos
Autores principales:	Mukherjee, A, Shehata, M, Moseley, P, Rakha, E, Ellis, I, Chan, S
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008601/ https://www.ncbi.nlm.nih.gov/pubmed/21063406 http://dx.doi.org/10.1038/sj.bjc.6605960

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