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Inherited polymorphisms in the RNA-mediated interference machinery affect microRNA expression and lung cancer survival

BACKGROUND: MicroRNAs (miRs) have an important role in lung carcinogenesis and progression. Single-nucleotide polymorphisms (SNPs) in genes involved in miR biogenesis may affect miR expression in lung tissue and be associated with lung carcinogenesis and progression. METHODS: We analysed 12 SNPs in...

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Detalles Bibliográficos
Autores principales:	Rotunno, M, Zhao, Y, Bergen, A W, Koshiol, J, Burdette, L, Rubagotti, M, Linnoila, R I, Marincola, F M, Bertazzi, P A, Pesatori, A C, Caporaso, N E, McShane, L M, Wang, E, Landi, M T
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008605/ https://www.ncbi.nlm.nih.gov/pubmed/21102586 http://dx.doi.org/10.1038/sj.bjc.6605976

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